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Do new cases of rheumatoid arthritis cluster in time or in space?

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Do new cases of rheumatoid arthritis cluster in time or in space? / Silman, A.; Bankhead, C.; Rowlingson, B. et al.
In: International Journal of Epidemiology, Vol. 26, No. 3, 1997, p. 628-634.

Research output: Contribution to Journal/MagazineJournal articlepeer-review

Harvard

Silman, A, Bankhead, C, Rowlingson, B, Brennan, P, Symmons, D & Gatrell, AC 1997, 'Do new cases of rheumatoid arthritis cluster in time or in space?', International Journal of Epidemiology, vol. 26, no. 3, pp. 628-634. https://doi.org/10.1093/ije/26.3.628

APA

Silman, A., Bankhead, C., Rowlingson, B., Brennan, P., Symmons, D., & Gatrell, A. C. (1997). Do new cases of rheumatoid arthritis cluster in time or in space? International Journal of Epidemiology, 26(3), 628-634. https://doi.org/10.1093/ije/26.3.628

Vancouver

Silman A, Bankhead C, Rowlingson B, Brennan P, Symmons D, Gatrell AC. Do new cases of rheumatoid arthritis cluster in time or in space? International Journal of Epidemiology. 1997;26(3):628-634. doi: 10.1093/ije/26.3.628

Author

Silman, A. ; Bankhead, C. ; Rowlingson, B. et al. / Do new cases of rheumatoid arthritis cluster in time or in space?. In: International Journal of Epidemiology. 1997 ; Vol. 26, No. 3. pp. 628-634.

Bibtex

@article{e010f032530f47bfabe8562c6943c413,
title = "Do new cases of rheumatoid arthritis cluster in time or in space?",
abstract = "OBJECTIVES: To examine for evidence of clustering in time, in space and in space/time in the occurrence of rheumatoid arthritis (RA). SETTING: A population-based incidence register of RA in the East Anglian region of the UK: population size 413,000. SUBJECTS: In all 687 new cases of inflammatory joint disease registered between 1 January 1990 and 31 December 1994 were studied. Population data were obtained from postcode areas by age and sex. ANALYSIS: Time trend analysis was conducted over the first 36 months and observed and expected distributions compared. Spatial clustering was based on comparison of observed distribution using map grid references to random expectation based on simulation. A similar procedure was undertaken for time/space clustering. RESULTS: There was no evidence of a time trend. There was only modest evidence of spatial clustering with non-random distribution observed in one area but there was no evidence of time/space clustering. CONCLUSION: Although a viral aetiology is the strongest candidate for RA, no evidence of a localized event in time was associated with disease development in this population.",
author = "A. Silman and C. Bankhead and B. Rowlingson and P. Brennan and D. Symmons and Gatrell, {A. C.}",
year = "1997",
doi = "10.1093/ije/26.3.628",
language = "English",
volume = "26",
pages = "628--634",
journal = "International Journal of Epidemiology",
publisher = "NLM (Medline)",
number = "3",

}

RIS

TY - JOUR

T1 - Do new cases of rheumatoid arthritis cluster in time or in space?

AU - Silman, A.

AU - Bankhead, C.

AU - Rowlingson, B.

AU - Brennan, P.

AU - Symmons, D.

AU - Gatrell, A. C.

PY - 1997

Y1 - 1997

N2 - OBJECTIVES: To examine for evidence of clustering in time, in space and in space/time in the occurrence of rheumatoid arthritis (RA). SETTING: A population-based incidence register of RA in the East Anglian region of the UK: population size 413,000. SUBJECTS: In all 687 new cases of inflammatory joint disease registered between 1 January 1990 and 31 December 1994 were studied. Population data were obtained from postcode areas by age and sex. ANALYSIS: Time trend analysis was conducted over the first 36 months and observed and expected distributions compared. Spatial clustering was based on comparison of observed distribution using map grid references to random expectation based on simulation. A similar procedure was undertaken for time/space clustering. RESULTS: There was no evidence of a time trend. There was only modest evidence of spatial clustering with non-random distribution observed in one area but there was no evidence of time/space clustering. CONCLUSION: Although a viral aetiology is the strongest candidate for RA, no evidence of a localized event in time was associated with disease development in this population.

AB - OBJECTIVES: To examine for evidence of clustering in time, in space and in space/time in the occurrence of rheumatoid arthritis (RA). SETTING: A population-based incidence register of RA in the East Anglian region of the UK: population size 413,000. SUBJECTS: In all 687 new cases of inflammatory joint disease registered between 1 January 1990 and 31 December 1994 were studied. Population data were obtained from postcode areas by age and sex. ANALYSIS: Time trend analysis was conducted over the first 36 months and observed and expected distributions compared. Spatial clustering was based on comparison of observed distribution using map grid references to random expectation based on simulation. A similar procedure was undertaken for time/space clustering. RESULTS: There was no evidence of a time trend. There was only modest evidence of spatial clustering with non-random distribution observed in one area but there was no evidence of time/space clustering. CONCLUSION: Although a viral aetiology is the strongest candidate for RA, no evidence of a localized event in time was associated with disease development in this population.

U2 - 10.1093/ije/26.3.628

DO - 10.1093/ije/26.3.628

M3 - Journal article

VL - 26

SP - 628

EP - 634

JO - International Journal of Epidemiology

JF - International Journal of Epidemiology

IS - 3

ER -