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Does phosphoenolpyruvate carboxykinase have a role in both amino acid and carbohydrate metabolism?

Research output: Contribution to Journal/Magazine › Journal article › peer-review

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Does phosphoenolpyruvate carboxykinase have a role in both amino acid and carbohydrate metabolism? / Lea, P. J.; Chen, Z.-H.; Leegood, R. C. et al.
In: Amino Acids, Vol. 20, No. 3, 04.2001, p. 225-241.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Lea, PJ, Chen, Z-H, Leegood, RC & Walker, RP 2001, 'Does phosphoenolpyruvate carboxykinase have a role in both amino acid and carbohydrate metabolism?', Amino Acids, vol. 20, no. 3, pp. 225-241. https://doi.org/10.1007/s007260170041

APA

Lea, P. J., Chen, Z.-H., Leegood, R. C., & Walker, R. P. (2001). Does phosphoenolpyruvate carboxykinase have a role in both amino acid and carbohydrate metabolism? Amino Acids, 20(3), 225-241. https://doi.org/10.1007/s007260170041

Vancouver

Lea PJ, Chen ZH, Leegood RC, Walker RP. Does phosphoenolpyruvate carboxykinase have a role in both amino acid and carbohydrate metabolism? Amino Acids. 2001 Apr;20(3):225-241. doi: 10.1007/s007260170041

Author

Lea, P. J. ; Chen, Z.-H. ; Leegood, R. C. et al. / Does phosphoenolpyruvate carboxykinase have a role in both amino acid and carbohydrate metabolism?. In: Amino Acids. 2001 ; Vol. 20, No. 3. pp. 225-241.

Bibtex

@article{1fbd23019cd6468faa05631163e549b0,
title = "Does phosphoenolpyruvate carboxykinase have a role in both amino acid and carbohydrate metabolism?",
abstract = "Phosphoenolpyruvate carboxykinase (PEPCK) catalyses the reversible decarboxylation of oxaloacetate to yield phosphoenolpyruvate and CO2. The role of the enzyme in gluconeogenesis and anaplerotic reactions in a range of organisms is discussed, along with the important function in C4 and CAM photosynthesis in higher plants. In addition, new data are presented indicating that PEPCK may play a key role in amino acid metabolism. It is proposed that PEPCK is involved in the conversion of the carbon skeleton of asparagine/aspartate (oxaloacetate) to that of glutamate/glutamine (2-oxoglutarate). This metabolism is particularly important in the transport system, seeds and fruits of higher plants.",
keywords = "Amino acid metabolism - Asparagine - Glutamate - Higher plants - Oxaloacetate - Phosphoenolpyruvate carboxykinase",
author = "Lea, {P. J.} and Z.-H. Chen and Leegood, {R. C.} and Walker, {R. P.}",
year = "2001",
month = apr,
doi = "10.1007/s007260170041",
language = "English",
volume = "20",
pages = "225--241",
journal = "Amino Acids",
issn = "0939-4451",
publisher = "Springer Wien",
number = "3",

}

RIS

TY - JOUR

T1 - Does phosphoenolpyruvate carboxykinase have a role in both amino acid and carbohydrate metabolism?

AU - Lea, P. J.

AU - Chen, Z.-H.

AU - Leegood, R. C.

AU - Walker, R. P.

PY - 2001/4

Y1 - 2001/4

N2 - Phosphoenolpyruvate carboxykinase (PEPCK) catalyses the reversible decarboxylation of oxaloacetate to yield phosphoenolpyruvate and CO2. The role of the enzyme in gluconeogenesis and anaplerotic reactions in a range of organisms is discussed, along with the important function in C4 and CAM photosynthesis in higher plants. In addition, new data are presented indicating that PEPCK may play a key role in amino acid metabolism. It is proposed that PEPCK is involved in the conversion of the carbon skeleton of asparagine/aspartate (oxaloacetate) to that of glutamate/glutamine (2-oxoglutarate). This metabolism is particularly important in the transport system, seeds and fruits of higher plants.

AB - Phosphoenolpyruvate carboxykinase (PEPCK) catalyses the reversible decarboxylation of oxaloacetate to yield phosphoenolpyruvate and CO2. The role of the enzyme in gluconeogenesis and anaplerotic reactions in a range of organisms is discussed, along with the important function in C4 and CAM photosynthesis in higher plants. In addition, new data are presented indicating that PEPCK may play a key role in amino acid metabolism. It is proposed that PEPCK is involved in the conversion of the carbon skeleton of asparagine/aspartate (oxaloacetate) to that of glutamate/glutamine (2-oxoglutarate). This metabolism is particularly important in the transport system, seeds and fruits of higher plants.

KW - Amino acid metabolism - Asparagine - Glutamate - Higher plants - Oxaloacetate - Phosphoenolpyruvate carboxykinase

U2 - 10.1007/s007260170041

DO - 10.1007/s007260170041

M3 - Journal article

VL - 20

SP - 225

EP - 241

JO - Amino Acids

JF - Amino Acids

SN - 0939-4451

IS - 3

ER -