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Dopamine and impairment at the executive level.

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<mark>Journal publication date</mark>08/1999
<mark>Journal</mark>Behavioral and Brain Sciences
Issue number4
Volume22
Number of pages2
Pages (from-to)678-679
Publication StatusPublished
<mark>Original language</mark>English

Abstract

Patients with schizophrenia have an impairment in the inhibition of reflexive saccades, as a consequence of a functional impairment of the prefrontal cortex, which has not yet been encapsulated in terms of a formal model. A number of novel and testable hypotheses can be generated from the framework proposed by Findlay & Walker that will stimulate further research. Their framework therefore marks an important step in the development of a comprehensive functional model of saccadic eye movements. Further advances will be assisted by (1) a recognition of important distinctions in the executive control of volitional saccades and (2) addressing the capacity for cross-model integration of spatial information in the generation of the spatial properties of saccadic eye movements.

Bibliographic note

http://journals.cambridge.org/action/displayJournal?jid=BBS The final, definitive version of this article has been published in the Journal, Behavioral and Brain Sciences, 22 (4), pp 678-679 1999, © 1999 Cambridge University Press.