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Drug orientations within statin-loaded lipoprotein nanoparticles by 19F solid-state NMR

Research output: Contribution to Journal/Magazine › Journal article › peer-review

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Drug orientations within statin-loaded lipoprotein nanoparticles by 19F solid-state NMR. / Lau, Sophie; Griffin, John; Hughes, Eleri et al.
In: Chemical Communications, Vol. 55, No. 88, 14.11.2019, p. 13287-13290.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Lau, S, Griffin, J, Hughes, E & Middleton, D 2019, 'Drug orientations within statin-loaded lipoprotein nanoparticles by 19F solid-state NMR', Chemical Communications, vol. 55, no. 88, pp. 13287-13290. https://doi.org/10.1039/C9CC05344A

APA

Lau, S., Griffin, J., Hughes, E., & Middleton, D. (2019). Drug orientations within statin-loaded lipoprotein nanoparticles by 19F solid-state NMR. Chemical Communications, 55(88), 13287-13290. https://doi.org/10.1039/C9CC05344A

Vancouver

Lau S, Griffin J, Hughes E, Middleton D. Drug orientations within statin-loaded lipoprotein nanoparticles by 19F solid-state NMR. Chemical Communications. 2019 Nov 14;55(88):13287-13290. Epub 2019 Oct 14. doi: 10.1039/C9CC05344A

Author

Lau, Sophie ; Griffin, John ; Hughes, Eleri et al. / Drug orientations within statin-loaded lipoprotein nanoparticles by 19F solid-state NMR. In: Chemical Communications. 2019 ; Vol. 55, No. 88. pp. 13287-13290.

Bibtex

@article{0e5741c64c984c3d83d1824a3ed044d9,
title = "Drug orientations within statin-loaded lipoprotein nanoparticles by 19F solid-state NMR",
abstract = "NMR measurements of 19F chemical shift anisotropy and 1H-19F dipolar couplings provide unprecedented information on the molecular orientations of two fluorine-containing statin drugs within the heterogeneous environment of reconstituted high-density lipoprotein (rHDL) nanoparticles, a drug delivery system under clinical investigation.",
author = "Sophie Lau and John Griffin and Eleri Hughes and David Middleton",
year = "2019",
month = nov,
day = "14",
doi = "10.1039/C9CC05344A",
language = "English",
volume = "55",
pages = "13287--13290",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "88",

}

RIS

TY - JOUR

T1 - Drug orientations within statin-loaded lipoprotein nanoparticles by 19F solid-state NMR

AU - Lau, Sophie

AU - Griffin, John

AU - Hughes, Eleri

AU - Middleton, David

PY - 2019/11/14

Y1 - 2019/11/14

N2 - NMR measurements of 19F chemical shift anisotropy and 1H-19F dipolar couplings provide unprecedented information on the molecular orientations of two fluorine-containing statin drugs within the heterogeneous environment of reconstituted high-density lipoprotein (rHDL) nanoparticles, a drug delivery system under clinical investigation.

AB - NMR measurements of 19F chemical shift anisotropy and 1H-19F dipolar couplings provide unprecedented information on the molecular orientations of two fluorine-containing statin drugs within the heterogeneous environment of reconstituted high-density lipoprotein (rHDL) nanoparticles, a drug delivery system under clinical investigation.

U2 - 10.1039/C9CC05344A

DO - 10.1039/C9CC05344A

M3 - Journal article

VL - 55

SP - 13287

EP - 13290

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 88

ER -