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Final published version
Research output: Book/Report/Proceedings › Other report
Research output: Book/Report/Proceedings › Other report
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TY - BOOK
T1 - Dynamics of cardiovascular ageing
AU - Stefanovska, Aneta
AU - McClintock, Peter V.E.
AU - Owen-Lynch, P. Jane
AU - Iatsenko, Dmytro
AU - Clarkson, P.M.B.
AU - Bernjak, Alan
N1 - Part of the final report of the joint Research Councils' New Dynamics of Ageing programme. .
PY - 2013
Y1 - 2013
N2 - We gain wrinkles and lose hair, as we age, but our bodies also change in less obvious but much more important ways. This project studied the age-relatedalterations that occur in the cardiovascular system – the heart, lungs and network of arteries and veins that carry oxygenated blood and nutrients to everycell of the body and remove the waste products of metabolism. It was already known that the phase of breathing affects the rate at which the heart beats, but that this effect decreases as we age. The research has associated this reduction in heart-lung interaction with changes in the endothelium, the inner lining of all the blood vessels. It involved making non-invasive measurements of blood flow in the skin of 200 healthy subjects of all ages. The analysis focused on very low frequency oscillations in blood flow that can give a measure of the state of the endothelium. The main conclusions are, first, that to age healthily, you should look after your endothelium and, secondly, that it should be feasible to design an instrument for assessing endothelial health – an endotheliometer.
AB - We gain wrinkles and lose hair, as we age, but our bodies also change in less obvious but much more important ways. This project studied the age-relatedalterations that occur in the cardiovascular system – the heart, lungs and network of arteries and veins that carry oxygenated blood and nutrients to everycell of the body and remove the waste products of metabolism. It was already known that the phase of breathing affects the rate at which the heart beats, but that this effect decreases as we age. The research has associated this reduction in heart-lung interaction with changes in the endothelium, the inner lining of all the blood vessels. It involved making non-invasive measurements of blood flow in the skin of 200 healthy subjects of all ages. The analysis focused on very low frequency oscillations in blood flow that can give a measure of the state of the endothelium. The main conclusions are, first, that to age healthily, you should look after your endothelium and, secondly, that it should be feasible to design an instrument for assessing endothelial health – an endotheliometer.
M3 - Other report
VL - NDA Findings 19
BT - Dynamics of cardiovascular ageing
PB - NDA Research Programme, University of Sheffield
CY - Sheffield
ER -