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Effect of calcium hydroxide on mechanical strength and biological properties of bioactive glass

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Effect of calcium hydroxide on mechanical strength and biological properties of bioactive glass. / Shah, A.T.; Batool, M.; Chaudhry, A.A.; Iqbal, F.; Javaid, A.; Zahid, S.; Ilyas, K.; bin Qasim, S.; Khan, A.F.; Khan, A.S.; ur Rehman, I.

In: Journal of the Mechanical Behavior of Biomedical Materials, Vol. 61, 01.08.2016, p. 617-626.

Research output: Contribution to journalJournal article

Harvard

Shah, AT, Batool, M, Chaudhry, AA, Iqbal, F, Javaid, A, Zahid, S, Ilyas, K, bin Qasim, S, Khan, AF, Khan, AS & ur Rehman, I 2016, 'Effect of calcium hydroxide on mechanical strength and biological properties of bioactive glass', Journal of the Mechanical Behavior of Biomedical Materials, vol. 61, pp. 617-626. https://doi.org/10.1016/j.jmbbm.2016.03.030

APA

Shah, A. T., Batool, M., Chaudhry, A. A., Iqbal, F., Javaid, A., Zahid, S., Ilyas, K., bin Qasim, S., Khan, A. F., Khan, A. S., & ur Rehman, I. (2016). Effect of calcium hydroxide on mechanical strength and biological properties of bioactive glass. Journal of the Mechanical Behavior of Biomedical Materials, 61, 617-626. https://doi.org/10.1016/j.jmbbm.2016.03.030

Vancouver

Shah AT, Batool M, Chaudhry AA, Iqbal F, Javaid A, Zahid S et al. Effect of calcium hydroxide on mechanical strength and biological properties of bioactive glass. Journal of the Mechanical Behavior of Biomedical Materials. 2016 Aug 1;61:617-626. https://doi.org/10.1016/j.jmbbm.2016.03.030

Author

Shah, A.T. ; Batool, M. ; Chaudhry, A.A. ; Iqbal, F. ; Javaid, A. ; Zahid, S. ; Ilyas, K. ; bin Qasim, S. ; Khan, A.F. ; Khan, A.S. ; ur Rehman, I. / Effect of calcium hydroxide on mechanical strength and biological properties of bioactive glass. In: Journal of the Mechanical Behavior of Biomedical Materials. 2016 ; Vol. 61. pp. 617-626.

Bibtex

@article{5bd3a154aced4f90ac25c7355d50af12,
title = "Effect of calcium hydroxide on mechanical strength and biological properties of bioactive glass",
abstract = "In this manuscript for the first time calcium hydroxide (Ca(OH)2) has been used for preparation of bioactive glass (BG-2) by co-precipitation method and compared with glass prepared using calcium nitrate tetrahydrate Ca(NO3)2·4H2O (BG-1), which is a conventional source of calcium. The new source positively affected physical, biological and mechanical properties of BG-2. The glasses were characterized by Fourier transform infrared (FTIR), X-Ray Diffractometer (XRD), Scanning Electron Microscopy (SEM), Thermogravimetric Analysis/Differential Scanning Calorimetry (TGA-DSC), BET surface area analysis and Knoop hardness. The results showed that BG-2 possessed relatively larger surface properties (100 m2 g-1 surface area) as compared to BG-1 (78 m2 g-1), spherical morphology and crystalline phases (wollastonite and apatite) after sintering at lower than conventional temperature. These properties contribute critical role in both mechanical and biological properties of glasses. The Knoop hardness measurements revealed that BG-2 possessed much better hardness (0.43±0.06 GPa at 680 °C and 2.16±0.46 GPa at 980 °C) than BG-1 (0.24±0.01 at 680 °C and 0.57±0.07GPA at 980 °C) under same conditions. Alamar blue Assay and confocal microscopy revealed that BG-2 exhibited better attachment and proliferation of MG63 cells. Based on the improved biological properties of BG-2 as a consequent of novel calcium source selection, BG-2 is proposed as a bioactive ceramic for hard tissue repair and regeneration applications.",
keywords = "Bioactive glass, Cytotoxicity, Hardness, Phase analysis, Structural analysis, Thermal behavior, Biomechanics, Calcium, Fourier transform infrared spectroscopy, Hydrated lime, Phosphate minerals, Precipitation (chemical), Scanning electron microscopy, Silicate minerals, Sintering, Surface properties, Thermogravimetric analysis, Tissue regeneration, Biological properties, Calcium nitrate tetra-hydrate, Coprecipitation method, Fourier transform infrared, Spherical morphologies, Thermal behaviors, X ray diffractometers, biomaterial, calcium hydroxide, calcium nitrate tetrahydrate, glass, unclassified drug, absorption, Article, biomechanics, comparative study, confocal microscopy, controlled study, decomposition, desorption, differential scanning calorimetry, glass transition temperature, hardness, human, human cell, infrared spectroscopy, osteoblast, osteosarcoma cell, physical chemistry, precipitation, priority journal, scanning electron microscopy, strength, stretching, surface area, surface property, thermogravimetry, tissue engineering, X ray diffraction, ceramics, chemistry, Biocompatible Materials, Calcium Hydroxide, Ceramics, Glass, Microscopy, Electron, Scanning, Spectroscopy, Fourier Transform Infrared, Surface Properties, X-Ray Diffraction",
author = "A.T. Shah and M. Batool and A.A. Chaudhry and F. Iqbal and A. Javaid and S. Zahid and K. Ilyas and {bin Qasim}, S. and A.F. Khan and A.S. Khan and {ur Rehman}, I.",
year = "2016",
month = aug
day = "1",
doi = "10.1016/j.jmbbm.2016.03.030",
language = "English",
volume = "61",
pages = "617--626",
journal = "Journal of the Mechanical Behavior of Biomedical Materials",
issn = "1751-6161",
publisher = "Elsevier Ltd",

}

RIS

TY - JOUR

T1 - Effect of calcium hydroxide on mechanical strength and biological properties of bioactive glass

AU - Shah, A.T.

AU - Batool, M.

AU - Chaudhry, A.A.

AU - Iqbal, F.

AU - Javaid, A.

AU - Zahid, S.

AU - Ilyas, K.

AU - bin Qasim, S.

AU - Khan, A.F.

AU - Khan, A.S.

AU - ur Rehman, I.

PY - 2016/8/1

Y1 - 2016/8/1

N2 - In this manuscript for the first time calcium hydroxide (Ca(OH)2) has been used for preparation of bioactive glass (BG-2) by co-precipitation method and compared with glass prepared using calcium nitrate tetrahydrate Ca(NO3)2·4H2O (BG-1), which is a conventional source of calcium. The new source positively affected physical, biological and mechanical properties of BG-2. The glasses were characterized by Fourier transform infrared (FTIR), X-Ray Diffractometer (XRD), Scanning Electron Microscopy (SEM), Thermogravimetric Analysis/Differential Scanning Calorimetry (TGA-DSC), BET surface area analysis and Knoop hardness. The results showed that BG-2 possessed relatively larger surface properties (100 m2 g-1 surface area) as compared to BG-1 (78 m2 g-1), spherical morphology and crystalline phases (wollastonite and apatite) after sintering at lower than conventional temperature. These properties contribute critical role in both mechanical and biological properties of glasses. The Knoop hardness measurements revealed that BG-2 possessed much better hardness (0.43±0.06 GPa at 680 °C and 2.16±0.46 GPa at 980 °C) than BG-1 (0.24±0.01 at 680 °C and 0.57±0.07GPA at 980 °C) under same conditions. Alamar blue Assay and confocal microscopy revealed that BG-2 exhibited better attachment and proliferation of MG63 cells. Based on the improved biological properties of BG-2 as a consequent of novel calcium source selection, BG-2 is proposed as a bioactive ceramic for hard tissue repair and regeneration applications.

AB - In this manuscript for the first time calcium hydroxide (Ca(OH)2) has been used for preparation of bioactive glass (BG-2) by co-precipitation method and compared with glass prepared using calcium nitrate tetrahydrate Ca(NO3)2·4H2O (BG-1), which is a conventional source of calcium. The new source positively affected physical, biological and mechanical properties of BG-2. The glasses were characterized by Fourier transform infrared (FTIR), X-Ray Diffractometer (XRD), Scanning Electron Microscopy (SEM), Thermogravimetric Analysis/Differential Scanning Calorimetry (TGA-DSC), BET surface area analysis and Knoop hardness. The results showed that BG-2 possessed relatively larger surface properties (100 m2 g-1 surface area) as compared to BG-1 (78 m2 g-1), spherical morphology and crystalline phases (wollastonite and apatite) after sintering at lower than conventional temperature. These properties contribute critical role in both mechanical and biological properties of glasses. The Knoop hardness measurements revealed that BG-2 possessed much better hardness (0.43±0.06 GPa at 680 °C and 2.16±0.46 GPa at 980 °C) than BG-1 (0.24±0.01 at 680 °C and 0.57±0.07GPA at 980 °C) under same conditions. Alamar blue Assay and confocal microscopy revealed that BG-2 exhibited better attachment and proliferation of MG63 cells. Based on the improved biological properties of BG-2 as a consequent of novel calcium source selection, BG-2 is proposed as a bioactive ceramic for hard tissue repair and regeneration applications.

KW - Bioactive glass

KW - Cytotoxicity

KW - Hardness

KW - Phase analysis

KW - Structural analysis

KW - Thermal behavior

KW - Biomechanics

KW - Calcium

KW - Fourier transform infrared spectroscopy

KW - Hydrated lime

KW - Phosphate minerals

KW - Precipitation (chemical)

KW - Scanning electron microscopy

KW - Silicate minerals

KW - Sintering

KW - Surface properties

KW - Thermogravimetric analysis

KW - Tissue regeneration

KW - Biological properties

KW - Calcium nitrate tetra-hydrate

KW - Coprecipitation method

KW - Fourier transform infrared

KW - Spherical morphologies

KW - Thermal behaviors

KW - X ray diffractometers

KW - biomaterial

KW - calcium hydroxide

KW - calcium nitrate tetrahydrate

KW - glass

KW - unclassified drug

KW - absorption

KW - Article

KW - biomechanics

KW - comparative study

KW - confocal microscopy

KW - controlled study

KW - decomposition

KW - desorption

KW - differential scanning calorimetry

KW - glass transition temperature

KW - hardness

KW - human

KW - human cell

KW - infrared spectroscopy

KW - osteoblast

KW - osteosarcoma cell

KW - physical chemistry

KW - precipitation

KW - priority journal

KW - scanning electron microscopy

KW - strength

KW - stretching

KW - surface area

KW - surface property

KW - thermogravimetry

KW - tissue engineering

KW - X ray diffraction

KW - ceramics

KW - chemistry

KW - Biocompatible Materials

KW - Calcium Hydroxide

KW - Ceramics

KW - Glass

KW - Microscopy, Electron, Scanning

KW - Spectroscopy, Fourier Transform Infrared

KW - Surface Properties

KW - X-Ray Diffraction

U2 - 10.1016/j.jmbbm.2016.03.030

DO - 10.1016/j.jmbbm.2016.03.030

M3 - Journal article

VL - 61

SP - 617

EP - 626

JO - Journal of the Mechanical Behavior of Biomedical Materials

JF - Journal of the Mechanical Behavior of Biomedical Materials

SN - 1751-6161

ER -