Final published version
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Electrical stimulation of human mesenchymal stem cells on conductive nanofibers enhances their differentiation toward osteogenic outcomes
AU - Hardy, John
AU - Villancio-Wolter, Maria
AU - Sukhavasi, Rushi
AU - Mouser, David
AU - Aguilar, David
AU - Geissler, Sydney
AU - Kaplan, David
AU - Schmidt, Christine
PY - 2015/11
Y1 - 2015/11
N2 - Tissue scaffolds allowing the behaviour of the cells that reside within them to be controlled are of particular interest for tissue engineering. Herein we describe the preparation of conductive fiber-based bone tissue scaffolds (nonwoven mats of electrospun polycaprolactone with an interpenetrating network of polypyrrole and polystyrenesulfonate) that enable the electrical stimulation of human mesenchymal stem cells to enhance their differentiation towards osteogenic outcomes.
AB - Tissue scaffolds allowing the behaviour of the cells that reside within them to be controlled are of particular interest for tissue engineering. Herein we describe the preparation of conductive fiber-based bone tissue scaffolds (nonwoven mats of electrospun polycaprolactone with an interpenetrating network of polypyrrole and polystyrenesulfonate) that enable the electrical stimulation of human mesenchymal stem cells to enhance their differentiation towards osteogenic outcomes.
KW - conducting polymers
KW - electrical stimulation
KW - tissue scaffold
KW - stem cells
KW - bone
KW - Bioengineering
KW - Electrochemistry
KW - Biomaterials
U2 - 10.1002/marc.201500233
DO - 10.1002/marc.201500233
M3 - Journal article
VL - 36
SP - 1884
EP - 1890
JO - Macromolecular Rapid Communications
JF - Macromolecular Rapid Communications
SN - 1022-1336
IS - 21
ER -