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Enhanced relapse prevention for bipolar disorder by community mental health teams: cluster feasibility randomised trial

Research output: Contribution to journalJournal article

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<mark>Journal publication date</mark>01/2010
<mark>Journal</mark>British Journal of Psychiatry
Issue number1
Volume196
Number of pages5
Pages (from-to)59-63
Publication statusPublished
Original languageEnglish

Abstract

Background

Relapse prevention for bipolar disorder increases time to relapse but is not available in routine practice.

Aims

To determine the feasibility and effectiveness of training community mental health teams (CMHTS) to deliver enhanced relapse prevention.

Method

in a cluster randomised controlled trial, CMHT workers were allocated to receive 12h training in enhanced relapse prevention to offer to people with bipolar disorder or to continue giving treatment as usual. The primary outcome was time to relapse and the secondary outcome was functioning.

Results

Twenty-three CMHTs and 96 service users took part. Compared with treatment as usual, enhanced relapse prevention increased median time to the next bipolar episode by 8.5 weeks (hazard ratio 0.79, 95% CI 0.45-1.38). Social and occupational functioning improved with the intervention (regression coefficient 0.68, 95% CI 0.05-1.32). The clustering effect was negligible but imprecise (intracluster correlation coefficient 0.0001, 95% CI 0.0000-0.5142).

Conclusions

Training care coordinators to offer enhanced relapse prevention for bipolar disorder may be a feasible effective treatment. Large-scale cluster trials are needed.