Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Enhanced relapse prevention for bipolar disorder by community mental health teams
T2 - cluster feasibility randomised trial
AU - Lobban, F.
AU - Taylor, L.
AU - Chandler, C.
AU - Tyler, Elizabeth
AU - Kinderman, P.
AU - Kolamunnage-Dona, R.
AU - Gamble, C.
AU - Peters, S.
AU - Pontin, E.
AU - Sellwood, William
AU - Morriss, R. K.
PY - 2010/1
Y1 - 2010/1
N2 - BackgroundRelapse prevention for bipolar disorder increases time to relapse but is not available in routine practice.AimsTo determine the feasibility and effectiveness of training community mental health teams (CMHTS) to deliver enhanced relapse prevention.Methodin a cluster randomised controlled trial, CMHT workers were allocated to receive 12h training in enhanced relapse prevention to offer to people with bipolar disorder or to continue giving treatment as usual. The primary outcome was time to relapse and the secondary outcome was functioning.ResultsTwenty-three CMHTs and 96 service users took part. Compared with treatment as usual, enhanced relapse prevention increased median time to the next bipolar episode by 8.5 weeks (hazard ratio 0.79, 95% CI 0.45-1.38). Social and occupational functioning improved with the intervention (regression coefficient 0.68, 95% CI 0.05-1.32). The clustering effect was negligible but imprecise (intracluster correlation coefficient 0.0001, 95% CI 0.0000-0.5142).ConclusionsTraining care coordinators to offer enhanced relapse prevention for bipolar disorder may be a feasible effective treatment. Large-scale cluster trials are needed.
AB - BackgroundRelapse prevention for bipolar disorder increases time to relapse but is not available in routine practice.AimsTo determine the feasibility and effectiveness of training community mental health teams (CMHTS) to deliver enhanced relapse prevention.Methodin a cluster randomised controlled trial, CMHT workers were allocated to receive 12h training in enhanced relapse prevention to offer to people with bipolar disorder or to continue giving treatment as usual. The primary outcome was time to relapse and the secondary outcome was functioning.ResultsTwenty-three CMHTs and 96 service users took part. Compared with treatment as usual, enhanced relapse prevention increased median time to the next bipolar episode by 8.5 weeks (hazard ratio 0.79, 95% CI 0.45-1.38). Social and occupational functioning improved with the intervention (regression coefficient 0.68, 95% CI 0.05-1.32). The clustering effect was negligible but imprecise (intracluster correlation coefficient 0.0001, 95% CI 0.0000-0.5142).ConclusionsTraining care coordinators to offer enhanced relapse prevention for bipolar disorder may be a feasible effective treatment. Large-scale cluster trials are needed.
KW - GROUP PSYCHOEDUCATION
KW - CARE
KW - IMPAIRMENT
KW - SYMPTOMS
KW - EFFICACY
UR - http://www.scopus.com/inward/record.url?scp=74949130860&partnerID=8YFLogxK
U2 - 10.1192/bjp.bp.109.065524
DO - 10.1192/bjp.bp.109.065524
M3 - Journal article
VL - 196
SP - 59
EP - 63
JO - British Journal of Psychiatry
JF - British Journal of Psychiatry
SN - 1472-1465
IS - 1
ER -