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Estimation of physiologic ability and surgical stress (E-PASS) as a predictor of immediate outcome after elective abdominal aortic aneurysm surgery

Research output: Contribution to journalJournal article

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  • Tjun Tang
  • S.R. Walsh
  • Thomas Fanshawe
  • J.H. Gillard
  • U. Sadat
  • K. Varty
  • M.E. Gaunt
  • J.R. Boyle
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<mark>Journal publication date</mark>08/2007
<mark>Journal</mark>American Journal of Surgery
Issue number2
Volume194
Number of pages7
Pages (from-to)176-182
Publication StatusPublished
<mark>Original language</mark>English

Abstract

Background
The Estimation of Physiologic Ability and Surgical Stress (E-PASS) score was designed on the premise that the balance between the patient’s physiologic reserve capacity and the surgical stress inflicted at operation was important in the occurrence of postoperative complications. The aim of this study was to assess its value in predicting mortality and morbidity after open elective abdominal aortic aneurysm (AAA) repair.

Methods
E-PASS data items were collected prospectively in a group of 204 patients undergoing elective open AAA repair over a 6-year period. The operative morbidity and mortality rates were compared with the preoperative risk score (PRS), surgical stress score (SSS) and comprehensive risk score (CRS) of E-PASS. The group comprised 180 (88%) males and the median age was 73 (range 44 to 86) years.

Results
There were 13 (6%) deaths and 121 (59%) experienced a postoperative complication. As the PRS, SSS and CRS increased, the incidence of postoperative morbidity and mortality significantly increased (P < .0001). Overall mean CRS was .52 (±.27). Mean CRS in the groups of patients who survived and died were .49 (±.24) and .98 (±26), respectively. PRS, SSS, and CRS all had extremely good predictive power for both mortality and morbidity as demonstrated by high areas under the receiver operator curve (range .799 to .953). CRS also showed a strong statistically significant association with the severity of postoperative complication (P < .0001) and length of hospital stay (P < .0001).

Conclusions
The E-PASS model appears to be a promising method of predicting death and the development of postoperative complications in patients undergoing elective open AAA surgery. It requires further validation in arterial surgery at different geographical locations.