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Expedient approach to chiral cyclobutanones: asymmetric synthesis of cyclobut-G

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Expedient approach to chiral cyclobutanones: asymmetric synthesis of cyclobut-G. / Darses, Benjamin; Greene, Andrew E.; Coote, Susannah C. et al.
In: Organic Letters, Vol. 10, No. 5, 06.03.2008, p. 821-824.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Darses, B, Greene, AE, Coote, SC & Poisson, J-F 2008, 'Expedient approach to chiral cyclobutanones: asymmetric synthesis of cyclobut-G', Organic Letters, vol. 10, no. 5, pp. 821-824. https://doi.org/10.1021/ol702977x

APA

Darses, B., Greene, A. E., Coote, S. C., & Poisson, J-F. (2008). Expedient approach to chiral cyclobutanones: asymmetric synthesis of cyclobut-G. Organic Letters, 10(5), 821-824. https://doi.org/10.1021/ol702977x

Vancouver

Darses B, Greene AE, Coote SC, Poisson J-F. Expedient approach to chiral cyclobutanones: asymmetric synthesis of cyclobut-G. Organic Letters. 2008 Mar 6;10(5):821-824. doi: 10.1021/ol702977x

Author

Darses, Benjamin ; Greene, Andrew E. ; Coote, Susannah C. et al. / Expedient approach to chiral cyclobutanones : asymmetric synthesis of cyclobut-G. In: Organic Letters. 2008 ; Vol. 10, No. 5. pp. 821-824.

Bibtex

@article{1cd375a7f64643aa847c5d9db9cedf2e,
title = "Expedient approach to chiral cyclobutanones: asymmetric synthesis of cyclobut-G",
abstract = "An efficient one-pot asymmetric synthesis of cyclobutanones from chiral enol ethers is described. The approach is illustrated with alkyl- and functionalized alkyl-substituted enol ethers (nine examples). A new enantioselective synthesis of cyclobut-G (Lobucavir) could thus be achieved.",
keywords = "ENANTIOSELECTIVE SYNTHESIS, CLAISEN REARRANGEMENT, 2+2 CYCLOADDITION, ENOL ETHERS, DICHLOROKETENE, CONSTRUCTION, NUCLEOSIDE, LOBUCAVIR, EFFICIENT, (+)-AMPHOROGYNINE-A",
author = "Benjamin Darses and Greene, {Andrew E.} and Coote, {Susannah C.} and Jean-Francois Poisson",
year = "2008",
month = mar,
day = "6",
doi = "10.1021/ol702977x",
language = "English",
volume = "10",
pages = "821--824",
journal = "Organic Letters",
issn = "1523-7060",
publisher = "American Chemical Society",
number = "5",

}

RIS

TY - JOUR

T1 - Expedient approach to chiral cyclobutanones

T2 - asymmetric synthesis of cyclobut-G

AU - Darses, Benjamin

AU - Greene, Andrew E.

AU - Coote, Susannah C.

AU - Poisson, Jean-Francois

PY - 2008/3/6

Y1 - 2008/3/6

N2 - An efficient one-pot asymmetric synthesis of cyclobutanones from chiral enol ethers is described. The approach is illustrated with alkyl- and functionalized alkyl-substituted enol ethers (nine examples). A new enantioselective synthesis of cyclobut-G (Lobucavir) could thus be achieved.

AB - An efficient one-pot asymmetric synthesis of cyclobutanones from chiral enol ethers is described. The approach is illustrated with alkyl- and functionalized alkyl-substituted enol ethers (nine examples). A new enantioselective synthesis of cyclobut-G (Lobucavir) could thus be achieved.

KW - ENANTIOSELECTIVE SYNTHESIS

KW - CLAISEN REARRANGEMENT

KW - 2+2 CYCLOADDITION

KW - ENOL ETHERS

KW - DICHLOROKETENE

KW - CONSTRUCTION

KW - NUCLEOSIDE

KW - LOBUCAVIR

KW - EFFICIENT

KW - (+)-AMPHOROGYNINE-A

U2 - 10.1021/ol702977x

DO - 10.1021/ol702977x

M3 - Journal article

VL - 10

SP - 821

EP - 824

JO - Organic Letters

JF - Organic Letters

SN - 1523-7060

IS - 5

ER -