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Fate of higher brominated PBDEs in lactating cows.

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Fate of higher brominated PBDEs in lactating cows. / Kierkegaard, Amelie; Asplund, Lillemor; de Wit, Cynthia A. et al.
In: Environmental Science and Technology, Vol. 41, No. 2, 15.01.2007, p. 417-423.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Kierkegaard, A, Asplund, L, de Wit, CA, McLachlan, MS, Thomas, GO, Sweetman, AJ & Jones, KC 2007, 'Fate of higher brominated PBDEs in lactating cows.', Environmental Science and Technology, vol. 41, no. 2, pp. 417-423. https://doi.org/10.1021/es0619197

APA

Kierkegaard, A., Asplund, L., de Wit, C. A., McLachlan, M. S., Thomas, G. O., Sweetman, A. J., & Jones, K. C. (2007). Fate of higher brominated PBDEs in lactating cows. Environmental Science and Technology, 41(2), 417-423. https://doi.org/10.1021/es0619197

Vancouver

Kierkegaard A, Asplund L, de Wit CA, McLachlan MS, Thomas GO, Sweetman AJ et al. Fate of higher brominated PBDEs in lactating cows. Environmental Science and Technology. 2007 Jan 15;41(2):417-423. doi: 10.1021/es0619197

Author

Kierkegaard, Amelie ; Asplund, Lillemor ; de Wit, Cynthia A. et al. / Fate of higher brominated PBDEs in lactating cows. In: Environmental Science and Technology. 2007 ; Vol. 41, No. 2. pp. 417-423.

Bibtex

@article{2d8a96c2884a4b74a5342ce574a9d2a7,
title = "Fate of higher brominated PBDEs in lactating cows.",
abstract = "Dietary intake studies of lower brominated diphenyl ethers (BDEs) have shown that fish and animal products are important vectors of human exposure, but almost no data exist for higher brominated BDEs. Therefore, the fate of hepta- to decaBDEs was studied in lactating cows exposed to a naturally contaminated diet by analyzing feed, feces, and milk samples from a previous mass balance study of PCB. Tissue distribution was studied in one cow slaughtered after the experiment. BDE-209 was the dominant congener in feed, organs, adipose tissues, and feces, but not in milk. In contrast to PCBs and lower brominated BDEs, concentrations of hepta- to decaBDEs in adipose tissue were 9−80 times higher than in milk fat and the difference increased with degree of bromination/log Kow. The congener profiles in adipose tissue and feed differed; BDE-207, BDE-196, BDE-197, and BDE-182 accumulated to a surprisingly greater extent in the fat compared to their isomers, suggesting metabolic debromination of BDE-209 to these BDEs. The results indicate that meat rather than dairy product consumption may be an important human exposure route to higher brominated BDEs.",
author = "Amelie Kierkegaard and Lillemor Asplund and {de Wit}, {Cynthia A.} and McLachlan, {Michael S.} and Thomas, {Gareth O.} and Sweetman, {Andrew J.} and Jones, {Kevin C.}",
year = "2007",
month = jan,
day = "15",
doi = "10.1021/es0619197",
language = "English",
volume = "41",
pages = "417--423",
journal = "Environmental Science and Technology",
issn = "0013-936X",
publisher = "American Chemical Society",
number = "2",

}

RIS

TY - JOUR

T1 - Fate of higher brominated PBDEs in lactating cows.

AU - Kierkegaard, Amelie

AU - Asplund, Lillemor

AU - de Wit, Cynthia A.

AU - McLachlan, Michael S.

AU - Thomas, Gareth O.

AU - Sweetman, Andrew J.

AU - Jones, Kevin C.

PY - 2007/1/15

Y1 - 2007/1/15

N2 - Dietary intake studies of lower brominated diphenyl ethers (BDEs) have shown that fish and animal products are important vectors of human exposure, but almost no data exist for higher brominated BDEs. Therefore, the fate of hepta- to decaBDEs was studied in lactating cows exposed to a naturally contaminated diet by analyzing feed, feces, and milk samples from a previous mass balance study of PCB. Tissue distribution was studied in one cow slaughtered after the experiment. BDE-209 was the dominant congener in feed, organs, adipose tissues, and feces, but not in milk. In contrast to PCBs and lower brominated BDEs, concentrations of hepta- to decaBDEs in adipose tissue were 9−80 times higher than in milk fat and the difference increased with degree of bromination/log Kow. The congener profiles in adipose tissue and feed differed; BDE-207, BDE-196, BDE-197, and BDE-182 accumulated to a surprisingly greater extent in the fat compared to their isomers, suggesting metabolic debromination of BDE-209 to these BDEs. The results indicate that meat rather than dairy product consumption may be an important human exposure route to higher brominated BDEs.

AB - Dietary intake studies of lower brominated diphenyl ethers (BDEs) have shown that fish and animal products are important vectors of human exposure, but almost no data exist for higher brominated BDEs. Therefore, the fate of hepta- to decaBDEs was studied in lactating cows exposed to a naturally contaminated diet by analyzing feed, feces, and milk samples from a previous mass balance study of PCB. Tissue distribution was studied in one cow slaughtered after the experiment. BDE-209 was the dominant congener in feed, organs, adipose tissues, and feces, but not in milk. In contrast to PCBs and lower brominated BDEs, concentrations of hepta- to decaBDEs in adipose tissue were 9−80 times higher than in milk fat and the difference increased with degree of bromination/log Kow. The congener profiles in adipose tissue and feed differed; BDE-207, BDE-196, BDE-197, and BDE-182 accumulated to a surprisingly greater extent in the fat compared to their isomers, suggesting metabolic debromination of BDE-209 to these BDEs. The results indicate that meat rather than dairy product consumption may be an important human exposure route to higher brominated BDEs.

U2 - 10.1021/es0619197

DO - 10.1021/es0619197

M3 - Journal article

VL - 41

SP - 417

EP - 423

JO - Environmental Science and Technology

JF - Environmental Science and Technology

SN - 0013-936X

IS - 2

ER -