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  • 2017_IB_Biospectra for microbiota review

    Rights statement: This journal is © The Royal Society of Chemistry 2017

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Fingerprinting microbiomes towards screening for microbial antibiotic resistance

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Fingerprinting microbiomes towards screening for microbial antibiotic resistance. / Jin, Naifu; Zhang, Dayi; Martin, Francis L.
In: Integrative Biology, Vol. 9, No. 5, 05.2017, p. 406-417.

Research output: Contribution to Journal/MagazineJournal articlepeer-review

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Jin N, Zhang D, Martin FL. Fingerprinting microbiomes towards screening for microbial antibiotic resistance. Integrative Biology. 2017 May;9(5):406-417. Epub 2017 Apr 27. doi: 10.1039/c7ib00009j

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@article{9475d2d146b34b0282a7c2b0ca4c350a,
title = "Fingerprinting microbiomes towards screening for microbial antibiotic resistance",
abstract = "There is an increasing need to investigate microbiomes in their entirety in a variety of contexts ranging from environmental to human health scenarios. This requirement is becoming increasingly important with the emergence of antibiotic resistance. In general, more conventional approaches are too expensive and/or time-consuming and often predicated on prior knowledge of the microorganisms one wishes to study. Herein, we propose the use of biospectroscopy tools as relatively high-throughput, non-destructive approaches to profile microbiomes under study. Fourier-transform infrared (FTIR) or Raman spectroscopy both generate fingerprint spectra of biological material and such spectra can readily be subsequently classed according to biochemical changes in the microbiota, such as emergence of antibiotic resistance. FTIR spectroscopy techniques generally can only be applied to desiccated material whereas Raman approaches can be applied to more hydrated samples. The ability to readily fingerprint microbiomes could lend itself to new approaches in determining microbial behaviours and emergence of antibiotic resistance.",
keywords = "Journal Article, Review",
author = "Naifu Jin and Dayi Zhang and Martin, {Francis L.}",
note = "This journal is {\textcopyright} The Royal Society of Chemistry 2017",
year = "2017",
month = may,
doi = "10.1039/c7ib00009j",
language = "English",
volume = "9",
pages = "406--417",
journal = "Integrative Biology",
issn = "1757-9694",
publisher = "Royal Society of Chemistry",
number = "5",

}

RIS

TY - JOUR

T1 - Fingerprinting microbiomes towards screening for microbial antibiotic resistance

AU - Jin, Naifu

AU - Zhang, Dayi

AU - Martin, Francis L.

N1 - This journal is © The Royal Society of Chemistry 2017

PY - 2017/5

Y1 - 2017/5

N2 - There is an increasing need to investigate microbiomes in their entirety in a variety of contexts ranging from environmental to human health scenarios. This requirement is becoming increasingly important with the emergence of antibiotic resistance. In general, more conventional approaches are too expensive and/or time-consuming and often predicated on prior knowledge of the microorganisms one wishes to study. Herein, we propose the use of biospectroscopy tools as relatively high-throughput, non-destructive approaches to profile microbiomes under study. Fourier-transform infrared (FTIR) or Raman spectroscopy both generate fingerprint spectra of biological material and such spectra can readily be subsequently classed according to biochemical changes in the microbiota, such as emergence of antibiotic resistance. FTIR spectroscopy techniques generally can only be applied to desiccated material whereas Raman approaches can be applied to more hydrated samples. The ability to readily fingerprint microbiomes could lend itself to new approaches in determining microbial behaviours and emergence of antibiotic resistance.

AB - There is an increasing need to investigate microbiomes in their entirety in a variety of contexts ranging from environmental to human health scenarios. This requirement is becoming increasingly important with the emergence of antibiotic resistance. In general, more conventional approaches are too expensive and/or time-consuming and often predicated on prior knowledge of the microorganisms one wishes to study. Herein, we propose the use of biospectroscopy tools as relatively high-throughput, non-destructive approaches to profile microbiomes under study. Fourier-transform infrared (FTIR) or Raman spectroscopy both generate fingerprint spectra of biological material and such spectra can readily be subsequently classed according to biochemical changes in the microbiota, such as emergence of antibiotic resistance. FTIR spectroscopy techniques generally can only be applied to desiccated material whereas Raman approaches can be applied to more hydrated samples. The ability to readily fingerprint microbiomes could lend itself to new approaches in determining microbial behaviours and emergence of antibiotic resistance.

KW - Journal Article

KW - Review

U2 - 10.1039/c7ib00009j

DO - 10.1039/c7ib00009j

M3 - Journal article

C2 - 28480939

VL - 9

SP - 406

EP - 417

JO - Integrative Biology

JF - Integrative Biology

SN - 1757-9694

IS - 5

ER -