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Glucose and memory: fractionation of enhancement effects?

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Glucose and memory: fractionation of enhancement effects? / Foster, J. K.; Lidder, P. G.; Sünram, S. I.
In: Psychopharmacology, Vol. 137, No. 3, 06.1998, p. 259-270.

Research output: Contribution to Journal/MagazineJournal articlepeer-review

Harvard

Foster, JK, Lidder, PG & Sünram, SI 1998, 'Glucose and memory: fractionation of enhancement effects?', Psychopharmacology, vol. 137, no. 3, pp. 259-270. https://doi.org/10.1007/s002130050619

APA

Foster, J. K., Lidder, P. G., & Sünram, S. I. (1998). Glucose and memory: fractionation of enhancement effects? Psychopharmacology, 137(3), 259-270. https://doi.org/10.1007/s002130050619

Vancouver

Foster JK, Lidder PG, Sünram SI. Glucose and memory: fractionation of enhancement effects? Psychopharmacology. 1998 Jun;137(3):259-270. doi: 10.1007/s002130050619

Author

Foster, J. K. ; Lidder, P. G. ; Sünram, S. I. / Glucose and memory : fractionation of enhancement effects?. In: Psychopharmacology. 1998 ; Vol. 137, No. 3. pp. 259-270.

Bibtex

@article{29ad2cffa59340a2a1d1bcf5f8f7f252,
title = "Glucose and memory: fractionation of enhancement effects?",
abstract = "Recent research findings indicate that glucose administration enhances some aspects of cognitive functioning. To date, those studies which have investigated the effects of glucose on memory in human participants have concentrated on its apparent ability to attenuate memory impairment. Relatively little research has been done in humans investigating the effects of glucose on memory performance in young healthy participants in whom no memory deficits exist. Moreover, the work which has been conducted in this population has produced somewhat equivocal findings. In this study, after overnight fasting the influence of a 25 g oral dosage of glucose on a range of measures of memory performance was investigated in healthy young female participants. Two control treatments (saccharin and water) were also administered. There was a significant glucose facilitation effect upon performance of long-term verbal free and cued recall tasks which did not vary with test delay. Performance on these free and cued verbal recall measures correlated significantly with blood glucose levels across all participants. No glucose-related facilitation was observed on either a test of short-term verbal memory (forwards/backwards digit recall) or a test of long-term non-verbal memory (complex figure reproduction). However, the significant glucose-related effects observed with long-term free and cued recall remained after controlling for participants{\textquoteright} differential baseline blood glucose levels and individual levels of immediate memory performance. Therefore, memory improvement after glucose ingestion was not merely a consequence of lower baseline blood glucose or lower immediate memory performance in the glucose treatment group. These findings indicate that there may be some fractionation in the memory facilitation effects of glucose: the memory enhancing effect of glucose administration in healthy young adults may be greatest on tests of long-term verbal recall. The results suggest that glucose may enhance retention in and/or retrieval from long-term verbal memory.",
keywords = "Glucose - Saccharin - Long-term memory - Short-term memory - Verbal memory - Non-verbal memory - Young control participants",
author = "Foster, {J. K.} and Lidder, {P. G.} and S{\"u}nram, {S. I.}",
year = "1998",
month = jun,
doi = "10.1007/s002130050619",
language = "English",
volume = "137",
pages = "259--270",
journal = "Psychopharmacology",
issn = "1432-2072",
publisher = "Springer",
number = "3",

}

RIS

TY - JOUR

T1 - Glucose and memory

T2 - fractionation of enhancement effects?

AU - Foster, J. K.

AU - Lidder, P. G.

AU - Sünram, S. I.

PY - 1998/6

Y1 - 1998/6

N2 - Recent research findings indicate that glucose administration enhances some aspects of cognitive functioning. To date, those studies which have investigated the effects of glucose on memory in human participants have concentrated on its apparent ability to attenuate memory impairment. Relatively little research has been done in humans investigating the effects of glucose on memory performance in young healthy participants in whom no memory deficits exist. Moreover, the work which has been conducted in this population has produced somewhat equivocal findings. In this study, after overnight fasting the influence of a 25 g oral dosage of glucose on a range of measures of memory performance was investigated in healthy young female participants. Two control treatments (saccharin and water) were also administered. There was a significant glucose facilitation effect upon performance of long-term verbal free and cued recall tasks which did not vary with test delay. Performance on these free and cued verbal recall measures correlated significantly with blood glucose levels across all participants. No glucose-related facilitation was observed on either a test of short-term verbal memory (forwards/backwards digit recall) or a test of long-term non-verbal memory (complex figure reproduction). However, the significant glucose-related effects observed with long-term free and cued recall remained after controlling for participants’ differential baseline blood glucose levels and individual levels of immediate memory performance. Therefore, memory improvement after glucose ingestion was not merely a consequence of lower baseline blood glucose or lower immediate memory performance in the glucose treatment group. These findings indicate that there may be some fractionation in the memory facilitation effects of glucose: the memory enhancing effect of glucose administration in healthy young adults may be greatest on tests of long-term verbal recall. The results suggest that glucose may enhance retention in and/or retrieval from long-term verbal memory.

AB - Recent research findings indicate that glucose administration enhances some aspects of cognitive functioning. To date, those studies which have investigated the effects of glucose on memory in human participants have concentrated on its apparent ability to attenuate memory impairment. Relatively little research has been done in humans investigating the effects of glucose on memory performance in young healthy participants in whom no memory deficits exist. Moreover, the work which has been conducted in this population has produced somewhat equivocal findings. In this study, after overnight fasting the influence of a 25 g oral dosage of glucose on a range of measures of memory performance was investigated in healthy young female participants. Two control treatments (saccharin and water) were also administered. There was a significant glucose facilitation effect upon performance of long-term verbal free and cued recall tasks which did not vary with test delay. Performance on these free and cued verbal recall measures correlated significantly with blood glucose levels across all participants. No glucose-related facilitation was observed on either a test of short-term verbal memory (forwards/backwards digit recall) or a test of long-term non-verbal memory (complex figure reproduction). However, the significant glucose-related effects observed with long-term free and cued recall remained after controlling for participants’ differential baseline blood glucose levels and individual levels of immediate memory performance. Therefore, memory improvement after glucose ingestion was not merely a consequence of lower baseline blood glucose or lower immediate memory performance in the glucose treatment group. These findings indicate that there may be some fractionation in the memory facilitation effects of glucose: the memory enhancing effect of glucose administration in healthy young adults may be greatest on tests of long-term verbal recall. The results suggest that glucose may enhance retention in and/or retrieval from long-term verbal memory.

KW - Glucose - Saccharin - Long-term memory - Short-term memory - Verbal memory - Non-verbal memory - Young control participants

U2 - 10.1007/s002130050619

DO - 10.1007/s002130050619

M3 - Journal article

VL - 137

SP - 259

EP - 270

JO - Psychopharmacology

JF - Psychopharmacology

SN - 1432-2072

IS - 3

ER -