We have over 12,000 students, from over 100 countries, within one of the safest campuses in the UK


97% of Lancaster students go into work or further study within six months of graduating

Home > Research > Publications & Outputs > Glutamate synthase and the synthesis of glutama...
View graph of relations

« Back

Glutamate synthase and the synthesis of glutamate in plants.

Research output: Contribution to journalJournal article


<mark>Journal publication date</mark>06/2003
<mark>Journal</mark>Plant Physiology and Biochemistry
Number of pages10
<mark>Original language</mark>English


The discovery of glutamate synthases (E.C. and E.C. caused a major re-assessment of the way in which ammonium is assimilated in bacteria and higher plants. The history of that discovery is reviewed and considered in the light of recent developments in the biochemistry and genetics of the higher plant ferredoxin- and NADH-dependent enzymes. The evidence is consistent with the view that plants synthesise glutamate from ammonia by the combined activity of glutamine synthetase (E.C. and glutamate synthase (the glutamate synthase cycle) and that glutamate dehydrogenase (GDH, E.C. plays no significant part in glutamate formation. The evidence does, however, suggest an important role for GDH as a catabolic shunt to ensure N metabolism does not adversely affect mitochondrial function and to enable the synthesis of N-rich transport compounds during nitrogen remobilisation.