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Highly efficient tetranuclear ZnII2LnIII2 catalysts for the friedel-crafts alkylation of indoles and nitrostyrenes

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  • Prashant Kumar
  • Smaragda Lymperopoulou
  • Kieran Griffiths
  • Stavroula I. Sampani
  • George E. Kostakis
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Article number140
<mark>Journal publication date</mark>12/09/2016
<mark>Journal</mark>Catalysts
Issue number9
Volume6
Publication StatusPublished
<mark>Original language</mark>English

Abstract

We demonstrate for the first time the high efficacy of tetranuclear ZnII2LnIII2 coordination clusters (CCs) as catalysts for the Friedel-Crafts (FC) alkylation of indoles with a range of trans-β-nitrostyrenes. The reaction proceeds in good to excellent yields (76%-99%) at room temperature with catalyst loadings as low as 1.0 mol %.