Home > Research > Publications & Outputs > Innate DNA sensing moves to the nucleus

Links

Text available via DOI:

View graph of relations

Innate DNA sensing moves to the nucleus

Research output: Contribution to journalJournal article

Published
<mark>Journal publication date</mark>19/05/2011
<mark>Journal</mark>Cell Host and Microbe
Issue number5
Volume9
Number of pages3
Pages (from-to)351-353
Publication StatusPublished
<mark>Original language</mark>English

Abstract

It has been assumed that cells distinguish viral from cellular DNA due to the former's presence in the cytosol. However, in this issue, Kerur et al. (2011) propose that the DNA genome of Kaposi's sarcoma-associated herpesvirus (KSHV) is recognized inside the nucleus by the DNA sensor IFI16, leading inflammasome activation.