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Intrinsic dynamics of heart regulatory systems on short timescales: from experiment to modelling.

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Intrinsic dynamics of heart regulatory systems on short timescales: from experiment to modelling. / Khovanov, I. A.; Khovanova, N. A.; McClintock, P. V. E. et al.
In: Journal of Statistical Mechanics: Theory and Experiment, Vol. P01016, 2009.

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Khovanov IA, Khovanova NA, McClintock PVE, Stefanovska A. Intrinsic dynamics of heart regulatory systems on short timescales: from experiment to modelling. Journal of Statistical Mechanics: Theory and Experiment. 2009;P01016. doi: 10.1088/1742-5468/2009/01/P01016

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Khovanov, I. A. ; Khovanova, N. A. ; McClintock, P. V. E. et al. / Intrinsic dynamics of heart regulatory systems on short timescales: from experiment to modelling. In: Journal of Statistical Mechanics: Theory and Experiment. 2009 ; Vol. P01016.

Bibtex

@article{e46d0f85f45f47b89c169f875972bc71,
title = "Intrinsic dynamics of heart regulatory systems on short timescales: from experiment to modelling.",
abstract = "We discuss open problems related to the stochastic modelling of cardiac function. The work is based on an experimental investigation of the dynamics of heart rate variability (HRV) in the absence of respiratory perturbations. We consider first the cardiac control system on short timescales via an analysis of HRV within the framework of a random walk approach. Our experiments show that HRV on timescales of less than a minute takes the form of free diffusion, close to Brownian motion, which can be described as a nonstationary process with stationary increments. Secondly, we consider the inverse problem of modelling the state of the control system so as to reproduce the experimentally observed HRV statistics of. We discuss some simple toy models and identify open problems for the modelling of heart dynamics.",
author = "Khovanov, {I. A.} and Khovanova, {N. A.} and McClintock, {P. V. E.} and A. Stefanovska",
year = "2009",
doi = "10.1088/1742-5468/2009/01/P01016",
language = "English",
volume = "P01016",
journal = "Journal of Statistical Mechanics: Theory and Experiment",
publisher = "IOP Publishing Ltd.",

}

RIS

TY - JOUR

T1 - Intrinsic dynamics of heart regulatory systems on short timescales: from experiment to modelling.

AU - Khovanov, I. A.

AU - Khovanova, N. A.

AU - McClintock, P. V. E.

AU - Stefanovska, A.

PY - 2009

Y1 - 2009

N2 - We discuss open problems related to the stochastic modelling of cardiac function. The work is based on an experimental investigation of the dynamics of heart rate variability (HRV) in the absence of respiratory perturbations. We consider first the cardiac control system on short timescales via an analysis of HRV within the framework of a random walk approach. Our experiments show that HRV on timescales of less than a minute takes the form of free diffusion, close to Brownian motion, which can be described as a nonstationary process with stationary increments. Secondly, we consider the inverse problem of modelling the state of the control system so as to reproduce the experimentally observed HRV statistics of. We discuss some simple toy models and identify open problems for the modelling of heart dynamics.

AB - We discuss open problems related to the stochastic modelling of cardiac function. The work is based on an experimental investigation of the dynamics of heart rate variability (HRV) in the absence of respiratory perturbations. We consider first the cardiac control system on short timescales via an analysis of HRV within the framework of a random walk approach. Our experiments show that HRV on timescales of less than a minute takes the form of free diffusion, close to Brownian motion, which can be described as a nonstationary process with stationary increments. Secondly, we consider the inverse problem of modelling the state of the control system so as to reproduce the experimentally observed HRV statistics of. We discuss some simple toy models and identify open problems for the modelling of heart dynamics.

U2 - 10.1088/1742-5468/2009/01/P01016

DO - 10.1088/1742-5468/2009/01/P01016

M3 - Journal article

VL - P01016

JO - Journal of Statistical Mechanics: Theory and Experiment

JF - Journal of Statistical Mechanics: Theory and Experiment

ER -