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    Rights statement: This is the author’s version of a work that was accepted for publication in Psychiatry Research. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Psychiatry Research, 285, 2020 DOI: 10.1016/j.psychres.2020.112806

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Is cognitive behavioural therapy effective for individuals experiencing thought disorder?

Research output: Contribution to journalJournal article

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Is cognitive behavioural therapy effective for individuals experiencing thought disorder? / Shryane, Nick; Drake, Richard; Morrison, Anthony P.; Palmier-Claus, Jasper.

In: Psychiatry Research, Vol. 285, 112806, 01.03.2020.

Research output: Contribution to journalJournal article

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Shryane, Nick ; Drake, Richard ; Morrison, Anthony P. ; Palmier-Claus, Jasper. / Is cognitive behavioural therapy effective for individuals experiencing thought disorder?. In: Psychiatry Research. 2020 ; Vol. 285.

Bibtex

@article{899a8c416245405eab86c4d1f2a5920a,
title = "Is cognitive behavioural therapy effective for individuals experiencing thought disorder?",
abstract = "Various clinical guidelines recommend cognitive behavioural therapy (CBT) to treat psychosis without reference to patients{\textquoteright} thought disorder. However, there is a risk that disorganized thinking hampers CBT. We tested the prediction that thought disorder would interfere with the effectiveness of CBT for hallucinations and delusions, compared to treatment as usual and supportive counselling, in secondary data from two large, single blind randomised controlled trials. We fitted latent growth curve models separately for the development of frequency and distress of symptoms. CBT was significantly more successful than counselling in reducing delusional frequency in the short term and hallucinatory distress at any point, even in those with relatively high thought disorder. We found little evidence that clinicians should restrict CBT in this subgroup of patients. Nevertheless, the findings highlight the importance of effective initial treatment of thought disorder in maximising the benefit of CBT for psychosis, particularly for reducing distress from hallucinations.",
keywords = "Psychosis, Cognitive Behavioural Therapy, Thought Disorder, Randomized Controlled Trial",
author = "Nick Shryane and Richard Drake and Morrison, {Anthony P.} and Jasper Palmier-Claus",
note = "This is the author{\textquoteright}s version of a work that was accepted for publication in Psychiatry Research. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Psychiatry Research, 285, 2020 DOI: 10.1016/j.psychres.2020.112806",
year = "2020",
month = mar,
day = "1",
doi = "10.1016/j.psychres.2020.112806",
language = "English",
volume = "285",
journal = "Psychiatry Research",
issn = "0165-1781",
publisher = "Elsevier Ireland Ltd",

}

RIS

TY - JOUR

T1 - Is cognitive behavioural therapy effective for individuals experiencing thought disorder?

AU - Shryane, Nick

AU - Drake, Richard

AU - Morrison, Anthony P.

AU - Palmier-Claus, Jasper

N1 - This is the author’s version of a work that was accepted for publication in Psychiatry Research. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Psychiatry Research, 285, 2020 DOI: 10.1016/j.psychres.2020.112806

PY - 2020/3/1

Y1 - 2020/3/1

N2 - Various clinical guidelines recommend cognitive behavioural therapy (CBT) to treat psychosis without reference to patients’ thought disorder. However, there is a risk that disorganized thinking hampers CBT. We tested the prediction that thought disorder would interfere with the effectiveness of CBT for hallucinations and delusions, compared to treatment as usual and supportive counselling, in secondary data from two large, single blind randomised controlled trials. We fitted latent growth curve models separately for the development of frequency and distress of symptoms. CBT was significantly more successful than counselling in reducing delusional frequency in the short term and hallucinatory distress at any point, even in those with relatively high thought disorder. We found little evidence that clinicians should restrict CBT in this subgroup of patients. Nevertheless, the findings highlight the importance of effective initial treatment of thought disorder in maximising the benefit of CBT for psychosis, particularly for reducing distress from hallucinations.

AB - Various clinical guidelines recommend cognitive behavioural therapy (CBT) to treat psychosis without reference to patients’ thought disorder. However, there is a risk that disorganized thinking hampers CBT. We tested the prediction that thought disorder would interfere with the effectiveness of CBT for hallucinations and delusions, compared to treatment as usual and supportive counselling, in secondary data from two large, single blind randomised controlled trials. We fitted latent growth curve models separately for the development of frequency and distress of symptoms. CBT was significantly more successful than counselling in reducing delusional frequency in the short term and hallucinatory distress at any point, even in those with relatively high thought disorder. We found little evidence that clinicians should restrict CBT in this subgroup of patients. Nevertheless, the findings highlight the importance of effective initial treatment of thought disorder in maximising the benefit of CBT for psychosis, particularly for reducing distress from hallucinations.

KW - Psychosis

KW - Cognitive Behavioural Therapy

KW - Thought Disorder

KW - Randomized Controlled Trial

U2 - 10.1016/j.psychres.2020.112806

DO - 10.1016/j.psychres.2020.112806

M3 - Journal article

VL - 285

JO - Psychiatry Research

JF - Psychiatry Research

SN - 0165-1781

M1 - 112806

ER -