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Kamin blocking is not disrupted by amphetamine in human subjects.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

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Kamin blocking is not disrupted by amphetamine in human subjects. / Gray, N. S.; Pickering, A. D.; Gray, J. A. et al.
In: Journal of Psychopharmacology, Vol. 11, No. 4, 1997, p. 301-311.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Gray, NS, Pickering, AD, Gray, JA, Jones, SH, Abrahams, S & Hemsley, DR 1997, 'Kamin blocking is not disrupted by amphetamine in human subjects.', Journal of Psychopharmacology, vol. 11, no. 4, pp. 301-311. https://doi.org/10.1177/026988119701100404

APA

Gray, N. S., Pickering, A. D., Gray, J. A., Jones, S. H., Abrahams, S., & Hemsley, D. R. (1997). Kamin blocking is not disrupted by amphetamine in human subjects. Journal of Psychopharmacology, 11(4), 301-311. https://doi.org/10.1177/026988119701100404

Vancouver

Gray NS, Pickering AD, Gray JA, Jones SH, Abrahams S, Hemsley DR. Kamin blocking is not disrupted by amphetamine in human subjects. Journal of Psychopharmacology. 1997;11(4):301-311. doi: 10.1177/026988119701100404

Author

Gray, N. S. ; Pickering, A. D. ; Gray, J. A. et al. / Kamin blocking is not disrupted by amphetamine in human subjects. In: Journal of Psychopharmacology. 1997 ; Vol. 11, No. 4. pp. 301-311.

Bibtex

@article{545349c15ec44b7eb01149b0b6b9db82,
title = "Kamin blocking is not disrupted by amphetamine in human subjects.",
abstract = "The effect of oral amphetamine administration on the Kamin-blocking effect in healthy volunteer subjects was investigated. Against predictions, Kamin blocking was not disrupted by either a high or low oral dose of D-amphetamine under conditions which have, in previous studies, led to disruption of a related learning phenomenon (latent inhibition). This lack of effect of amphetamine administration upon Kamin blocking weakens hypotheses that this cognitive process is mediated by the same changes in dopaminergic activity which affect latent inhibition. Currently, the only data which show strong comparative associations between Kamin blocking and latent inhibition are when they are applied to schizophrenic populations. These results may suggest that Kamin blocking and latent inhibition may be measuring different aspects of schizophrenic cognitive dysfunction.",
keywords = "amphetamine • Kamin-blocking effect • schizophrenia",
author = "Gray, {N. S.} and Pickering, {A. D.} and Gray, {J. A.} and Jones, {Steven H.} and S. Abrahams and Hemsley, {D. R.}",
year = "1997",
doi = "10.1177/026988119701100404",
language = "English",
volume = "11",
pages = "301--311",
journal = "Journal of Psychopharmacology",
issn = "1461-7285",
publisher = "SAGE Publications Ltd",
number = "4",

}

RIS

TY - JOUR

T1 - Kamin blocking is not disrupted by amphetamine in human subjects.

AU - Gray, N. S.

AU - Pickering, A. D.

AU - Gray, J. A.

AU - Jones, Steven H.

AU - Abrahams, S.

AU - Hemsley, D. R.

PY - 1997

Y1 - 1997

N2 - The effect of oral amphetamine administration on the Kamin-blocking effect in healthy volunteer subjects was investigated. Against predictions, Kamin blocking was not disrupted by either a high or low oral dose of D-amphetamine under conditions which have, in previous studies, led to disruption of a related learning phenomenon (latent inhibition). This lack of effect of amphetamine administration upon Kamin blocking weakens hypotheses that this cognitive process is mediated by the same changes in dopaminergic activity which affect latent inhibition. Currently, the only data which show strong comparative associations between Kamin blocking and latent inhibition are when they are applied to schizophrenic populations. These results may suggest that Kamin blocking and latent inhibition may be measuring different aspects of schizophrenic cognitive dysfunction.

AB - The effect of oral amphetamine administration on the Kamin-blocking effect in healthy volunteer subjects was investigated. Against predictions, Kamin blocking was not disrupted by either a high or low oral dose of D-amphetamine under conditions which have, in previous studies, led to disruption of a related learning phenomenon (latent inhibition). This lack of effect of amphetamine administration upon Kamin blocking weakens hypotheses that this cognitive process is mediated by the same changes in dopaminergic activity which affect latent inhibition. Currently, the only data which show strong comparative associations between Kamin blocking and latent inhibition are when they are applied to schizophrenic populations. These results may suggest that Kamin blocking and latent inhibition may be measuring different aspects of schizophrenic cognitive dysfunction.

KW - amphetamine • Kamin-blocking effect • schizophrenia

U2 - 10.1177/026988119701100404

DO - 10.1177/026988119701100404

M3 - Journal article

VL - 11

SP - 301

EP - 311

JO - Journal of Psychopharmacology

JF - Journal of Psychopharmacology

SN - 1461-7285

IS - 4

ER -