Rights statement: This is the peer reviewed version of the following article: Harrison R, Criss ZK, Feller L, Modi SP, Hardy JG, Schmidt CE, Suggs LJ, Murphy MB. 2016. Mechanical properties of α-tricalcium phosphate-based bone cements incorporating regenerative biomaterials for filling bone defects exposed to low mechanical loads. J Biomed Mater Res Part B 2016:104B:149–157 which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1002/jbm.b.33362/abstract This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.
Accepted author manuscript, 158 KB, PDF document
Rights statement: This is the peer reviewed version of the following article: Harrison R, Criss ZK, Feller L, Modi SP, Hardy JG, Schmidt CE, Suggs LJ, Murphy MB. 2016. Mechanical properties of α-tricalcium phosphate-based bone cements incorporating regenerative biomaterials for filling bone defects exposed to low mechanical loads. J Biomed Mater Res Part B 2016:104B:149–157 which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1002/jbm.b.33362/abstract This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.
Accepted author manuscript, 440 KB, PDF document
Final published version
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
}
TY - JOUR
T1 - Mechanical properties of α-tricalcium phosphate-based bone cements incorporating regenerative biomaterials for filling bone defects exposed to low mechanical loads
AU - Harrison, Reed
AU - Criss, Zachary K.
AU - Feller, Lacie
AU - Modi, Shan P.
AU - Hardy, John G.
AU - Schmidt, Christine E.
AU - Suggs, Laura J.
AU - Murphy, Matthew B.
N1 - This is the peer reviewed version of the following article: Chrisman, J. J., Fang, H., Kotlar, J. and De Massis, A. (2014), A Note on Family Influence and the Adoption of Discontinuous Technologies in Family Firms. Journal of Product Innovation Management. doi: 10.1111/jpim.12206 which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1111/jpim.12206/abstract This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.
PY - 2016/1
Y1 - 2016/1
N2 - Calcium phosphate-based cements with enhanced regenerative potential are promising biomaterials for the healing of bone defects. With a view to the use of such cements for low load bearing applications such as sinus augmentation or filling extraction sites, we have prepared α-tricalcium phosphate (α-TCP)-based bone cements including materials that we would expect to improve their regenerative potential, and describe the mechanical properities of the resulting formulations herein. Formulations incorporated α-TCP, hydroxyapatite, biopolymer-thickened wetting agents, sutures, and platelet poor plasma. The mechanical properties of the composites were composition dependent, and optimized formulations had clinically relevant mechanical properties. Such calcium phosphate-based cements have potential as replacements for cements such as those based on polymethylmethacrylate (PMMA).
AB - Calcium phosphate-based cements with enhanced regenerative potential are promising biomaterials for the healing of bone defects. With a view to the use of such cements for low load bearing applications such as sinus augmentation or filling extraction sites, we have prepared α-tricalcium phosphate (α-TCP)-based bone cements including materials that we would expect to improve their regenerative potential, and describe the mechanical properities of the resulting formulations herein. Formulations incorporated α-TCP, hydroxyapatite, biopolymer-thickened wetting agents, sutures, and platelet poor plasma. The mechanical properties of the composites were composition dependent, and optimized formulations had clinically relevant mechanical properties. Such calcium phosphate-based cements have potential as replacements for cements such as those based on polymethylmethacrylate (PMMA).
KW - Biodegradation
KW - BIOMATERIALS
KW - COMPOSITE
KW - Minerals
KW - Biomaterials
KW - Ceramics and Composites
U2 - 10.1002/jbm.b.33362
DO - 10.1002/jbm.b.33362
M3 - Journal article
VL - 104
SP - 149
EP - 157
JO - Journal of Biomedical Materials Research Part B: Applied Biomaterials
JF - Journal of Biomedical Materials Research Part B: Applied Biomaterials
SN - 1552-4973
IS - 1
ER -