Home > Research > Publications & Outputs > Mitochondrial replacement

Research

Associated organisational unit

Electronic data

  • Mitochondrial replacement REVISED FINAL SUBMISSION FOR BIOETHICS (May 2015)

    Accepted author manuscript, 462 KB, PDF document

    Available under license: CC BY-NC: Creative Commons Attribution-NonCommercial 4.0 International License

  • Wrigley_et_al-2015-Bioethics

    Rights statement: © 2015 The Authors. Bioethics published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

    Final published version, 106 KB, PDF document

    Available under license: CC BY: Creative Commons Attribution 4.0 International License

Links

Text available via DOI:

View graph of relations

Mitochondrial replacement: ethics and identity

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Published

Standard

Mitochondrial replacement: ethics and identity. / Wrigley, Anthony; Wilkinson, Stephen; Appleby, John.
In: Bioethics, Vol. 29, No. 9, 11.2015, p. 631-638.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Wrigley, A, Wilkinson, S & Appleby, J 2015, 'Mitochondrial replacement: ethics and identity', Bioethics, vol. 29, no. 9, pp. 631-638. https://doi.org/10.1111/bioe.12187

APA

Wrigley, A., Wilkinson, S., & Appleby, J. (2015). Mitochondrial replacement: ethics and identity. Bioethics, 29(9), 631-638. https://doi.org/10.1111/bioe.12187

Vancouver

Wrigley A, Wilkinson S, Appleby J. Mitochondrial replacement: ethics and identity. Bioethics. 2015 Nov;29(9):631-638. Epub 2015 Oct 19. doi: 10.1111/bioe.12187

Author

Wrigley, Anthony ; Wilkinson, Stephen ; Appleby, John. / Mitochondrial replacement : ethics and identity. In: Bioethics. 2015 ; Vol. 29, No. 9. pp. 631-638.

Bibtex

@article{84f4f63d32ff41fe8e36d71482ef8b72,
title = "Mitochondrial replacement: ethics and identity",
abstract = "Mitochondrial replacement techniques (MRTs) have the potential to allow prospective parents who are at risk of passing on debilitating or even life-threatening mitochondrial disorders to have healthy children to whom they are genetically related. Ethical concerns have however been raised about these techniques. This article focuses on one aspect of the ethical debate, the question of whether there is any moral difference between the two types of MRT proposed: Pronuclear Transfer (PNT) and Maternal Spindle Transfer (MST). It examines how questions of identity impact on the ethical evaluation of each technique and argues that there is an important difference between the two. PNT, it is argued, is a form of therapy based on embryo modification while MST is, instead, an instance of selective reproduction. The article's main ethical conclusion is that, in some circumstances, there is a stronger obligation to use PNT than MST.",
author = "Anthony Wrigley and Stephen Wilkinson and John Appleby",
note = "{\textcopyright} 2015 The Authors. Bioethics published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.",
year = "2015",
month = nov,
doi = "10.1111/bioe.12187",
language = "English",
volume = "29",
pages = "631--638",
journal = "Bioethics",
issn = "0269-9702",
publisher = "Wiley-Blackwell",
number = "9",

}

RIS

TY - JOUR

T1 - Mitochondrial replacement

T2 - ethics and identity

AU - Wrigley, Anthony

AU - Wilkinson, Stephen

AU - Appleby, John

N1 - © 2015 The Authors. Bioethics published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

PY - 2015/11

Y1 - 2015/11

N2 - Mitochondrial replacement techniques (MRTs) have the potential to allow prospective parents who are at risk of passing on debilitating or even life-threatening mitochondrial disorders to have healthy children to whom they are genetically related. Ethical concerns have however been raised about these techniques. This article focuses on one aspect of the ethical debate, the question of whether there is any moral difference between the two types of MRT proposed: Pronuclear Transfer (PNT) and Maternal Spindle Transfer (MST). It examines how questions of identity impact on the ethical evaluation of each technique and argues that there is an important difference between the two. PNT, it is argued, is a form of therapy based on embryo modification while MST is, instead, an instance of selective reproduction. The article's main ethical conclusion is that, in some circumstances, there is a stronger obligation to use PNT than MST.

AB - Mitochondrial replacement techniques (MRTs) have the potential to allow prospective parents who are at risk of passing on debilitating or even life-threatening mitochondrial disorders to have healthy children to whom they are genetically related. Ethical concerns have however been raised about these techniques. This article focuses on one aspect of the ethical debate, the question of whether there is any moral difference between the two types of MRT proposed: Pronuclear Transfer (PNT) and Maternal Spindle Transfer (MST). It examines how questions of identity impact on the ethical evaluation of each technique and argues that there is an important difference between the two. PNT, it is argued, is a form of therapy based on embryo modification while MST is, instead, an instance of selective reproduction. The article's main ethical conclusion is that, in some circumstances, there is a stronger obligation to use PNT than MST.

U2 - 10.1111/bioe.12187

DO - 10.1111/bioe.12187

M3 - Journal article

VL - 29

SP - 631

EP - 638

JO - Bioethics

JF - Bioethics

SN - 0269-9702

IS - 9

ER -