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Monitoring changes in malaria epidemiology and effectiveness of interventions in Ethiopia and Uganda: Beyond Garki Project baseline survey

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Monitoring changes in malaria epidemiology and effectiveness of interventions in Ethiopia and Uganda : Beyond Garki Project baseline survey. / Abeku, Tarekegn A; Helinski, Michelle E H; Kirby, Matthew J; Kefyalew, Takele; Awano, Tessema; Batisso, Esey; Tesfaye, Gezahegn; Ssekitooleko, James; Nicholas, Sarala; Erdmanis, Laura; Nalwoga, Angela; Bass, Chris; Cose, Stephen; Assefa, Ashenafi; Kebede, Zelalem; Habte, Tedila; Katamba, Vincent; Nuwa, Anthony; Bakeera-Ssali, Stella; Akiror, Sarah C; Kyomuhangi, Irene; Tekalegne, Agonafer; Magumba, Godfrey; Meek, Sylvia R.

In: Malaria Journal, Vol. 14, 337, 04.09.2015.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Abeku, TA, Helinski, MEH, Kirby, MJ, Kefyalew, T, Awano, T, Batisso, E, Tesfaye, G, Ssekitooleko, J, Nicholas, S, Erdmanis, L, Nalwoga, A, Bass, C, Cose, S, Assefa, A, Kebede, Z, Habte, T, Katamba, V, Nuwa, A, Bakeera-Ssali, S, Akiror, SC, Kyomuhangi, I, Tekalegne, A, Magumba, G & Meek, SR 2015, 'Monitoring changes in malaria epidemiology and effectiveness of interventions in Ethiopia and Uganda: Beyond Garki Project baseline survey', Malaria Journal, vol. 14, 337. https://doi.org/10.1186/s12936-015-0852-7

APA

Abeku, T. A., Helinski, M. E. H., Kirby, M. J., Kefyalew, T., Awano, T., Batisso, E., Tesfaye, G., Ssekitooleko, J., Nicholas, S., Erdmanis, L., Nalwoga, A., Bass, C., Cose, S., Assefa, A., Kebede, Z., Habte, T., Katamba, V., Nuwa, A., Bakeera-Ssali, S., ... Meek, S. R. (2015). Monitoring changes in malaria epidemiology and effectiveness of interventions in Ethiopia and Uganda: Beyond Garki Project baseline survey. Malaria Journal, 14, [337]. https://doi.org/10.1186/s12936-015-0852-7

Vancouver

Author

Abeku, Tarekegn A ; Helinski, Michelle E H ; Kirby, Matthew J ; Kefyalew, Takele ; Awano, Tessema ; Batisso, Esey ; Tesfaye, Gezahegn ; Ssekitooleko, James ; Nicholas, Sarala ; Erdmanis, Laura ; Nalwoga, Angela ; Bass, Chris ; Cose, Stephen ; Assefa, Ashenafi ; Kebede, Zelalem ; Habte, Tedila ; Katamba, Vincent ; Nuwa, Anthony ; Bakeera-Ssali, Stella ; Akiror, Sarah C ; Kyomuhangi, Irene ; Tekalegne, Agonafer ; Magumba, Godfrey ; Meek, Sylvia R. / Monitoring changes in malaria epidemiology and effectiveness of interventions in Ethiopia and Uganda : Beyond Garki Project baseline survey. In: Malaria Journal. 2015 ; Vol. 14.

Bibtex

@article{ffb60d14dd7a445ebd1762afa80b689f,
title = "Monitoring changes in malaria epidemiology and effectiveness of interventions in Ethiopia and Uganda: Beyond Garki Project baseline survey",
abstract = "BACKGROUND: Scale-up of malaria interventions seems to have contributed to a decline in the disease but other factors may also have had some role. Understanding changes in transmission and determinant factors will help to adapt control strategies accordingly.METHODS: Four sites in Ethiopia and Uganda were set up to monitor epidemiological changes and effectiveness of interventions over time. Here, results of a survey during the peak transmission season of 2012 are reported, which will be used as baseline for subsequent surveys and may support adaptation of control strategies. Data on malariometric and entomological variables, socio-economic status (SES) and control coverage were collected.RESULTS: Malaria prevalence varied from 1.4 % in Guba (Ethiopia) to 9.9 % in Butemba (Uganda). The most dominant species was Plasmodium vivax in Ethiopia and Plasmodium falciparum in Uganda. The majority of human-vector contact occurred indoors in Uganda, ranging from 83 % (Anopheles funestus sensu lato) to 93 % (Anopheles gambiae s.l.), which is an important factor for the effectiveness of insecticide-treated nets (ITNs) or indoor residual spraying (IRS). High kdr-L1014S (resistance genotype) frequency was observed in A. gambiae sensu stricto in Uganda. Too few mosquitoes were collected in Ethiopia, so it was not possible to assess vector habits and insecticide resistance levels. ITN ownership did not vary by SES and 56-98 % and 68-78 % of households owned at least one ITN in Ethiopia and Uganda, respectively. In Uganda, 7 % of nets were purchased by households, but the nets were untreated. In three of the four sites, 69-76 % of people with access to ITNs used them. IRS coverage ranged from 84 to 96 % in the three sprayed sites. Half of febrile children in Uganda and three-quarters in Ethiopia for whom treatment was sought received diagnostic tests. High levels of child undernutrition were detected in both countries carrying important implications on child development. In Uganda, 7-8 % of pregnant women took the recommended minimum three doses of intermittent preventive treatment.CONCLUSION: Malaria epidemiology seems to be changing compared to earlier published data, and it is essential to have more data to understand how much of the changes are attributable to interventions and other factors. Regular monitoring will help to better interpret changes, identify determinants, modify strategies and improve targeting to address transmission heterogeneity.",
keywords = "Adolescent, Adult, Anemia, Animals, Anopheles, Child, Child, Preschool, Cross-Sectional Studies, Ethiopia/epidemiology, Female, Fever, Health Knowledge, Attitudes, Practice, Humans, Infant, Infant, Newborn, Insect Vectors, Insecticides, Malaria/epidemiology, Male, Malnutrition, Mosquito Control, Plasmodium falciparum, Plasmodium vivax, Pregnancy, Pregnancy Complications, Prevalence, Uganda/epidemiology, Young Adult",
author = "Abeku, {Tarekegn A} and Helinski, {Michelle E H} and Kirby, {Matthew J} and Takele Kefyalew and Tessema Awano and Esey Batisso and Gezahegn Tesfaye and James Ssekitooleko and Sarala Nicholas and Laura Erdmanis and Angela Nalwoga and Chris Bass and Stephen Cose and Ashenafi Assefa and Zelalem Kebede and Tedila Habte and Vincent Katamba and Anthony Nuwa and Stella Bakeera-Ssali and Akiror, {Sarah C} and Irene Kyomuhangi and Agonafer Tekalegne and Godfrey Magumba and Meek, {Sylvia R}",
year = "2015",
month = sep,
day = "4",
doi = "10.1186/s12936-015-0852-7",
language = "English",
volume = "14",
journal = "Malaria Journal",
issn = "1475-2875",
publisher = "BioMed Central",

}

RIS

TY - JOUR

T1 - Monitoring changes in malaria epidemiology and effectiveness of interventions in Ethiopia and Uganda

T2 - Beyond Garki Project baseline survey

AU - Abeku, Tarekegn A

AU - Helinski, Michelle E H

AU - Kirby, Matthew J

AU - Kefyalew, Takele

AU - Awano, Tessema

AU - Batisso, Esey

AU - Tesfaye, Gezahegn

AU - Ssekitooleko, James

AU - Nicholas, Sarala

AU - Erdmanis, Laura

AU - Nalwoga, Angela

AU - Bass, Chris

AU - Cose, Stephen

AU - Assefa, Ashenafi

AU - Kebede, Zelalem

AU - Habte, Tedila

AU - Katamba, Vincent

AU - Nuwa, Anthony

AU - Bakeera-Ssali, Stella

AU - Akiror, Sarah C

AU - Kyomuhangi, Irene

AU - Tekalegne, Agonafer

AU - Magumba, Godfrey

AU - Meek, Sylvia R

PY - 2015/9/4

Y1 - 2015/9/4

N2 - BACKGROUND: Scale-up of malaria interventions seems to have contributed to a decline in the disease but other factors may also have had some role. Understanding changes in transmission and determinant factors will help to adapt control strategies accordingly.METHODS: Four sites in Ethiopia and Uganda were set up to monitor epidemiological changes and effectiveness of interventions over time. Here, results of a survey during the peak transmission season of 2012 are reported, which will be used as baseline for subsequent surveys and may support adaptation of control strategies. Data on malariometric and entomological variables, socio-economic status (SES) and control coverage were collected.RESULTS: Malaria prevalence varied from 1.4 % in Guba (Ethiopia) to 9.9 % in Butemba (Uganda). The most dominant species was Plasmodium vivax in Ethiopia and Plasmodium falciparum in Uganda. The majority of human-vector contact occurred indoors in Uganda, ranging from 83 % (Anopheles funestus sensu lato) to 93 % (Anopheles gambiae s.l.), which is an important factor for the effectiveness of insecticide-treated nets (ITNs) or indoor residual spraying (IRS). High kdr-L1014S (resistance genotype) frequency was observed in A. gambiae sensu stricto in Uganda. Too few mosquitoes were collected in Ethiopia, so it was not possible to assess vector habits and insecticide resistance levels. ITN ownership did not vary by SES and 56-98 % and 68-78 % of households owned at least one ITN in Ethiopia and Uganda, respectively. In Uganda, 7 % of nets were purchased by households, but the nets were untreated. In three of the four sites, 69-76 % of people with access to ITNs used them. IRS coverage ranged from 84 to 96 % in the three sprayed sites. Half of febrile children in Uganda and three-quarters in Ethiopia for whom treatment was sought received diagnostic tests. High levels of child undernutrition were detected in both countries carrying important implications on child development. In Uganda, 7-8 % of pregnant women took the recommended minimum three doses of intermittent preventive treatment.CONCLUSION: Malaria epidemiology seems to be changing compared to earlier published data, and it is essential to have more data to understand how much of the changes are attributable to interventions and other factors. Regular monitoring will help to better interpret changes, identify determinants, modify strategies and improve targeting to address transmission heterogeneity.

AB - BACKGROUND: Scale-up of malaria interventions seems to have contributed to a decline in the disease but other factors may also have had some role. Understanding changes in transmission and determinant factors will help to adapt control strategies accordingly.METHODS: Four sites in Ethiopia and Uganda were set up to monitor epidemiological changes and effectiveness of interventions over time. Here, results of a survey during the peak transmission season of 2012 are reported, which will be used as baseline for subsequent surveys and may support adaptation of control strategies. Data on malariometric and entomological variables, socio-economic status (SES) and control coverage were collected.RESULTS: Malaria prevalence varied from 1.4 % in Guba (Ethiopia) to 9.9 % in Butemba (Uganda). The most dominant species was Plasmodium vivax in Ethiopia and Plasmodium falciparum in Uganda. The majority of human-vector contact occurred indoors in Uganda, ranging from 83 % (Anopheles funestus sensu lato) to 93 % (Anopheles gambiae s.l.), which is an important factor for the effectiveness of insecticide-treated nets (ITNs) or indoor residual spraying (IRS). High kdr-L1014S (resistance genotype) frequency was observed in A. gambiae sensu stricto in Uganda. Too few mosquitoes were collected in Ethiopia, so it was not possible to assess vector habits and insecticide resistance levels. ITN ownership did not vary by SES and 56-98 % and 68-78 % of households owned at least one ITN in Ethiopia and Uganda, respectively. In Uganda, 7 % of nets were purchased by households, but the nets were untreated. In three of the four sites, 69-76 % of people with access to ITNs used them. IRS coverage ranged from 84 to 96 % in the three sprayed sites. Half of febrile children in Uganda and three-quarters in Ethiopia for whom treatment was sought received diagnostic tests. High levels of child undernutrition were detected in both countries carrying important implications on child development. In Uganda, 7-8 % of pregnant women took the recommended minimum three doses of intermittent preventive treatment.CONCLUSION: Malaria epidemiology seems to be changing compared to earlier published data, and it is essential to have more data to understand how much of the changes are attributable to interventions and other factors. Regular monitoring will help to better interpret changes, identify determinants, modify strategies and improve targeting to address transmission heterogeneity.

KW - Adolescent

KW - Adult

KW - Anemia

KW - Animals

KW - Anopheles

KW - Child

KW - Child, Preschool

KW - Cross-Sectional Studies

KW - Ethiopia/epidemiology

KW - Female

KW - Fever

KW - Health Knowledge, Attitudes, Practice

KW - Humans

KW - Infant

KW - Infant, Newborn

KW - Insect Vectors

KW - Insecticides

KW - Malaria/epidemiology

KW - Male

KW - Malnutrition

KW - Mosquito Control

KW - Plasmodium falciparum

KW - Plasmodium vivax

KW - Pregnancy

KW - Pregnancy Complications

KW - Prevalence

KW - Uganda/epidemiology

KW - Young Adult

U2 - 10.1186/s12936-015-0852-7

DO - 10.1186/s12936-015-0852-7

M3 - Journal article

C2 - 26337671

VL - 14

JO - Malaria Journal

JF - Malaria Journal

SN - 1475-2875

M1 - 337

ER -