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    Rights statement: This is the peer reviewed version of the following article: Lin K-M, Ehrgott M. Multiobjective navigation of external radiotherapy plans based on clinical criteria. J Multi-Crit Decis Anal. 2018;25:31–41. https://doi.org/10.1002/mcda.1628 which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1002/mcda.1628/abstract This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.

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Multiobjective navigation of external radiotherapy plans based on clinical criteria

Research output: Contribution to journalJournal article

Published
<mark>Journal publication date</mark>01/2018
<mark>Journal</mark>Journal of Multi-Criteria Decision Analysis
Issue number1-2
Volume25
Number of pages11
Pages (from-to)31-41
Publication statusPublished
Early online date12/10/17
Original languageEnglish

Abstract

This study considers a navigation method for finding the most preferable radiotherapy plan from a discrete set using planner-defined clinical criteria. The method is based on repeatedly solving an optimisation model to identify a plan that best satisfies the aspiration values set by the planner. During navigation, the planner iteratively adjusts the aspiration values to match the preference information learned from previous plans until the most preferable plan is identified. The use of soft constraints to model aspiration values enables navigation among a discrete set and allows the planner to freely specify the aspiration values without producing an infeasible model. We demonstrate the use of the model by applying it to a prostate cancer case. This illustrates that improvements in optimisation criteria do not necessarily lead to improvements in clinical criteria. Hence the method obviates the need to simultaneously monitor both optimisation and clinical criteria in current navigation systems. Instead, the direct use of clinical criteria for navigation aids the planner to quickly identify the most preferable plan.

Bibliographic note

This is the peer reviewed version of the following article: Lin K-M, Ehrgott M. Multiobjective navigation of external radiotherapy plans based on clinical criteria. J Multi-Crit Decis Anal. 2018;25:31–41. https://doi.org/10.1002/mcda.1628 which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1002/mcda.1628/abstract This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.