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Novel antibiotics: second generation macrocyclic peptides designed to trap Holliday junctions

Research output: Contribution to Journal/Magazine › Journal article › peer-review

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Novel antibiotics: second generation macrocyclic peptides designed to trap Holliday junctions. / Liotta, Lisa; Medina, Irene; Robinson, Jennifer et al.
In: Tetrahedron Letters, Vol. 45, No. 46, 08.11.2004, p. 8447-8450.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Liotta, L, Medina, I, Robinson, J, Carroll, C, Pan, P-S, Corral, R, Johnston, J, Cook, K, Curtis, F, Sharples, G & McAlpine, S 2004, 'Novel antibiotics: second generation macrocyclic peptides designed to trap Holliday junctions', Tetrahedron Letters, vol. 45, no. 46, pp. 8447-8450. https://doi.org/10.1016/j.tetlet.2004.09.084

APA

Liotta, L., Medina, I., Robinson, J., Carroll, C., Pan, P-S., Corral, R., Johnston, J., Cook, K., Curtis, F., Sharples, G., & McAlpine, S. (2004). Novel antibiotics: second generation macrocyclic peptides designed to trap Holliday junctions. Tetrahedron Letters, 45(46), 8447-8450. https://doi.org/10.1016/j.tetlet.2004.09.084

Vancouver

Liotta L, Medina I, Robinson J, Carroll C, Pan P-S, Corral R et al. Novel antibiotics: second generation macrocyclic peptides designed to trap Holliday junctions. Tetrahedron Letters. 2004 Nov 8;45(46):8447-8450. doi: 10.1016/j.tetlet.2004.09.084

Author

Liotta, Lisa ; Medina, Irene ; Robinson, Jennifer et al. / Novel antibiotics: second generation macrocyclic peptides designed to trap Holliday junctions. In: Tetrahedron Letters. 2004 ; Vol. 45, No. 46. pp. 8447-8450.

Bibtex

@article{ac3f99cb811746039844252a7a6c094c,
title = "Novel antibiotics: second generation macrocyclic peptides designed to trap Holliday junctions",
abstract = "Described are the syntheses of 15 macrocyclic peptides designed to trap Holliday junctions (HJs) in bacteria during site-specific and homologous recombination. This leads to inhibiting bacterial growth. These second generation macrocycles were based on the C-2 symmetrical HJ. They were synthesized using a strategy that permits elucidation of the amino acid role in binding HJs. The syntheses of these macrocycles are an important step in the development of a new class of antibiotics.",
author = "Lisa Liotta and Irene Medina and Jennifer Robinson and Chris Carroll and Po-Shen Pan and Ricardo Corral and Jennifer Johnston and Kristina Cook and Fiona Curtis and Gary Sharples and Shelli McAlpine",
year = "2004",
month = nov,
day = "8",
doi = "10.1016/j.tetlet.2004.09.084",
language = "English",
volume = "45",
pages = "8447--8450",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Ltd",
number = "46",

}

RIS

TY - JOUR

T1 - Novel antibiotics: second generation macrocyclic peptides designed to trap Holliday junctions

AU - Liotta, Lisa

AU - Medina, Irene

AU - Robinson, Jennifer

AU - Carroll, Chris

AU - Pan, Po-Shen

AU - Corral, Ricardo

AU - Johnston, Jennifer

AU - Cook, Kristina

AU - Curtis, Fiona

AU - Sharples, Gary

AU - McAlpine, Shelli

PY - 2004/11/8

Y1 - 2004/11/8

N2 - Described are the syntheses of 15 macrocyclic peptides designed to trap Holliday junctions (HJs) in bacteria during site-specific and homologous recombination. This leads to inhibiting bacterial growth. These second generation macrocycles were based on the C-2 symmetrical HJ. They were synthesized using a strategy that permits elucidation of the amino acid role in binding HJs. The syntheses of these macrocycles are an important step in the development of a new class of antibiotics.

AB - Described are the syntheses of 15 macrocyclic peptides designed to trap Holliday junctions (HJs) in bacteria during site-specific and homologous recombination. This leads to inhibiting bacterial growth. These second generation macrocycles were based on the C-2 symmetrical HJ. They were synthesized using a strategy that permits elucidation of the amino acid role in binding HJs. The syntheses of these macrocycles are an important step in the development of a new class of antibiotics.

U2 - 10.1016/j.tetlet.2004.09.084

DO - 10.1016/j.tetlet.2004.09.084

M3 - Journal article

VL - 45

SP - 8447

EP - 8450

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 46

ER -