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Perfect Simulation From Nonneutral Population Genetic Models: Variable Population Size and Population Subdivision.

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Perfect Simulation From Nonneutral Population Genetic Models: Variable Population Size and Population Subdivision. / Fearnhead, Paul.
In: Genetics, Vol. 174, 11.2006, p. 1397-1406.

Research output: Contribution to Journal/MagazineJournal articlepeer-review

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@article{32c2f199686947df923aaa0317d7ff03,
title = "Perfect Simulation From Nonneutral Population Genetic Models: Variable Population Size and Population Subdivision.",
abstract = "We show how the idea of monotone coupling from the past can produce simple algorithms for simulating samples at a nonneutral locus under a range of demographic models. We specifically consider a biallelic locus and either a general variable population size mode or a general migration model for population subdivision. We investigate the effect of demography on the efficacy of selection and the effect of selection on genetic divergence between populations.",
author = "Paul Fearnhead",
year = "2006",
month = nov,
doi = "10.1534/genetics.106.060681",
language = "English",
volume = "174",
pages = "1397--1406",
journal = "Genetics",
issn = "1943-2631",
publisher = "Genetics Society of America",

}

RIS

TY - JOUR

T1 - Perfect Simulation From Nonneutral Population Genetic Models: Variable Population Size and Population Subdivision.

AU - Fearnhead, Paul

PY - 2006/11

Y1 - 2006/11

N2 - We show how the idea of monotone coupling from the past can produce simple algorithms for simulating samples at a nonneutral locus under a range of demographic models. We specifically consider a biallelic locus and either a general variable population size mode or a general migration model for population subdivision. We investigate the effect of demography on the efficacy of selection and the effect of selection on genetic divergence between populations.

AB - We show how the idea of monotone coupling from the past can produce simple algorithms for simulating samples at a nonneutral locus under a range of demographic models. We specifically consider a biallelic locus and either a general variable population size mode or a general migration model for population subdivision. We investigate the effect of demography on the efficacy of selection and the effect of selection on genetic divergence between populations.

U2 - 10.1534/genetics.106.060681

DO - 10.1534/genetics.106.060681

M3 - Journal article

VL - 174

SP - 1397

EP - 1406

JO - Genetics

JF - Genetics

SN - 1943-2631

ER -