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PFAS health effects database: Protocol for a systematic evidence map

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PFAS health effects database: Protocol for a systematic evidence map. / Pelch, K.E.; Reade, A.; Wolffe, T.A.M. et al.
In: Environment International, Vol. 130, 104851, 01.09.2019.

Research output: Contribution to Journal/MagazineJournal articlepeer-review

Harvard

Pelch, KE, Reade, A, Wolffe, TAM & Kwiatkowski, CF 2019, 'PFAS health effects database: Protocol for a systematic evidence map', Environment International, vol. 130, 104851. https://doi.org/10.1016/j.envint.2019.05.045

APA

Pelch, K. E., Reade, A., Wolffe, T. A. M., & Kwiatkowski, C. F. (2019). PFAS health effects database: Protocol for a systematic evidence map. Environment International, 130, Article 104851. https://doi.org/10.1016/j.envint.2019.05.045

Vancouver

Pelch KE, Reade A, Wolffe TAM, Kwiatkowski CF. PFAS health effects database: Protocol for a systematic evidence map. Environment International. 2019 Sept 1;130:104851. Epub 2019 Jul 5. doi: 10.1016/j.envint.2019.05.045

Author

Pelch, K.E. ; Reade, A. ; Wolffe, T.A.M. et al. / PFAS health effects database : Protocol for a systematic evidence map. In: Environment International. 2019 ; Vol. 130.

Bibtex

@article{39a9974f22d046cfb57caba66ccf66ac,
title = "PFAS health effects database: Protocol for a systematic evidence map",
abstract = "Background: Per- and polyfluoroalkyl substances (PFAS) confer waterproof, greaseproof, and non-stick properties when added to consumer products. They are also used for industrial purposes including in aqueous film forming foams for firefighting. PFAS are ubiquitous in the environment, are widely detected in human biomonitoring studies, and are of growing regulatory concern across federal, state, and local governments. Regulators, scientists, and citizens need to stay informed on the growing health and toxicology literature related to PFAS. Objectives: The goal of this systematic evidence map is to identify and organize the available health and toxicology related literature on a set of 29 PFAS of emerging and growing concern. Search and study eligibility: We will search the electronic database PubMed for health or toxicological studies on 29 PFAS of emerging concern. Eligible studies must contain primary research investigating the link between one or more of the PFAS of interest and a health effect, toxicological, or biological mechanistic endpoint. Study appraisal and synthesis methods: Title and abstract screening and full text review will require a single reviewer for inclusion to the next level and two independent reviewers for exclusion. Study quality will not be conducted for this evidence mapping. Study characteristics will be extracted and coded from the included studies and checked for accuracy by a second reviewer. The extracted and coded information will be visualized in a publicly available, interactive database hosted on Tableau Public. Results of the evidence mapping will be published in a narrative summary. ",
keywords = "Per- and polyfluoroalkyl substances, PFAS, Systematic evidence map, Toxicology",
author = "K.E. Pelch and A. Reade and T.A.M. Wolffe and C.F. Kwiatkowski",
year = "2019",
month = sep,
day = "1",
doi = "10.1016/j.envint.2019.05.045",
language = "English",
volume = "130",
journal = "Environment International",
issn = "0160-4120",
publisher = "Elsevier Ltd",

}

RIS

TY - JOUR

T1 - PFAS health effects database

T2 - Protocol for a systematic evidence map

AU - Pelch, K.E.

AU - Reade, A.

AU - Wolffe, T.A.M.

AU - Kwiatkowski, C.F.

PY - 2019/9/1

Y1 - 2019/9/1

N2 - Background: Per- and polyfluoroalkyl substances (PFAS) confer waterproof, greaseproof, and non-stick properties when added to consumer products. They are also used for industrial purposes including in aqueous film forming foams for firefighting. PFAS are ubiquitous in the environment, are widely detected in human biomonitoring studies, and are of growing regulatory concern across federal, state, and local governments. Regulators, scientists, and citizens need to stay informed on the growing health and toxicology literature related to PFAS. Objectives: The goal of this systematic evidence map is to identify and organize the available health and toxicology related literature on a set of 29 PFAS of emerging and growing concern. Search and study eligibility: We will search the electronic database PubMed for health or toxicological studies on 29 PFAS of emerging concern. Eligible studies must contain primary research investigating the link between one or more of the PFAS of interest and a health effect, toxicological, or biological mechanistic endpoint. Study appraisal and synthesis methods: Title and abstract screening and full text review will require a single reviewer for inclusion to the next level and two independent reviewers for exclusion. Study quality will not be conducted for this evidence mapping. Study characteristics will be extracted and coded from the included studies and checked for accuracy by a second reviewer. The extracted and coded information will be visualized in a publicly available, interactive database hosted on Tableau Public. Results of the evidence mapping will be published in a narrative summary.

AB - Background: Per- and polyfluoroalkyl substances (PFAS) confer waterproof, greaseproof, and non-stick properties when added to consumer products. They are also used for industrial purposes including in aqueous film forming foams for firefighting. PFAS are ubiquitous in the environment, are widely detected in human biomonitoring studies, and are of growing regulatory concern across federal, state, and local governments. Regulators, scientists, and citizens need to stay informed on the growing health and toxicology literature related to PFAS. Objectives: The goal of this systematic evidence map is to identify and organize the available health and toxicology related literature on a set of 29 PFAS of emerging and growing concern. Search and study eligibility: We will search the electronic database PubMed for health or toxicological studies on 29 PFAS of emerging concern. Eligible studies must contain primary research investigating the link between one or more of the PFAS of interest and a health effect, toxicological, or biological mechanistic endpoint. Study appraisal and synthesis methods: Title and abstract screening and full text review will require a single reviewer for inclusion to the next level and two independent reviewers for exclusion. Study quality will not be conducted for this evidence mapping. Study characteristics will be extracted and coded from the included studies and checked for accuracy by a second reviewer. The extracted and coded information will be visualized in a publicly available, interactive database hosted on Tableau Public. Results of the evidence mapping will be published in a narrative summary.

KW - Per- and polyfluoroalkyl substances

KW - PFAS

KW - Systematic evidence map

KW - Toxicology

U2 - 10.1016/j.envint.2019.05.045

DO - 10.1016/j.envint.2019.05.045

M3 - Journal article

VL - 130

JO - Environment International

JF - Environment International

SN - 0160-4120

M1 - 104851

ER -