Final published version
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Preparation and characterization of a novel bioactive restorative composite based on covalently coupled polyurethane-nanohydroxyapatite fibres
AU - Khan, A.S.
AU - Ahmad, Z.
AU - Edirisinghe, M.J.
AU - Wong, F.S.L.
AU - Rehman, I.U.
PY - 2008
Y1 - 2008
N2 - Nanohydroxyapatite (n-HAp) was prepared using a sol-gel method. n-HAp powder was obtained from the gel form by heat treatment followed by grinding using ball milling. A novel polyurethane composite material was prepared by chemically binding the hydroxyapatite to the diisocyanate component in the polyurethane backbone through solvent polymerization. The procedure involved the stepwise addition of monomeric units of the polyurethane and optimizing the reagent concentrations. The resultant composite material was electrospun to form fibre mats. The fibres were less than 1 μm in thickness and contained no beads or irregularities. Chemical structural characterization of both the ceramics and the novel polymers were carried out by Fourier transform infrared and Raman spectroscopy. X-ray diffraction, scanning electron microscopy (SEM), transmission electron microscopy and Brunauer-Emmett-Teller surface area analysis were also employed to observe the crystal lattice and size and surface area of the n-HAp. Further characterization (by energy-dispersive X-ray analysis and SEM) of the spun fibres revealed the presence of elements associated with hydroxyapatite and polyurethane without the presence of any loose particles of hydroxyapatite, indicating the formation of the covalent bond between the ceramics and the polymer backbone. © 2008 Acta Materialia Inc.
AB - Nanohydroxyapatite (n-HAp) was prepared using a sol-gel method. n-HAp powder was obtained from the gel form by heat treatment followed by grinding using ball milling. A novel polyurethane composite material was prepared by chemically binding the hydroxyapatite to the diisocyanate component in the polyurethane backbone through solvent polymerization. The procedure involved the stepwise addition of monomeric units of the polyurethane and optimizing the reagent concentrations. The resultant composite material was electrospun to form fibre mats. The fibres were less than 1 μm in thickness and contained no beads or irregularities. Chemical structural characterization of both the ceramics and the novel polymers were carried out by Fourier transform infrared and Raman spectroscopy. X-ray diffraction, scanning electron microscopy (SEM), transmission electron microscopy and Brunauer-Emmett-Teller surface area analysis were also employed to observe the crystal lattice and size and surface area of the n-HAp. Further characterization (by energy-dispersive X-ray analysis and SEM) of the spun fibres revealed the presence of elements associated with hydroxyapatite and polyurethane without the presence of any loose particles of hydroxyapatite, indicating the formation of the covalent bond between the ceramics and the polymer backbone. © 2008 Acta Materialia Inc.
KW - Electrospun fibres
KW - FTIR and Raman spectroscopy
KW - Hydroxyapatite
KW - Polyurethane
KW - SEM
KW - hydroxyapatite
KW - nanohydroxyapatite
KW - polymer
KW - polyurethan
KW - reagent
KW - solvent
KW - addition reaction
KW - article
KW - ceramics
KW - chemical binding
KW - chemical structure
KW - composite material
KW - covalent bond
KW - crystal structure
KW - gel
KW - heat treatment
KW - infrared spectroscopy
KW - polymerization
KW - powder
KW - priority journal
KW - Raman spectrometry
KW - scanning electron microscopy
KW - transmission electron microscopy
KW - X ray diffraction
U2 - 10.1016/j.actbio.2008.04.016
DO - 10.1016/j.actbio.2008.04.016
M3 - Journal article
VL - 4
SP - 1275
EP - 1287
JO - Acta Biomaterialia
JF - Acta Biomaterialia
SN - 1742-7061
IS - 5
ER -