Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Reaction workup planning
T2 - A structured flowchart approach, exemplified in difficult aqueous workup of hydrophilic products
AU - Hill, George B.
AU - Sweeney, Joseph B.
PY - 2015/3/10
Y1 - 2015/3/10
N2 - Reaction workup can be a complex problem for those facing novel synthesis of difficult compounds for the first time. Workup problem solving by systematic thinking should be inculcated as mid-graduate-level is reached. A structured approach is proposed, building decision tree flowcharts to analyze challenges, and an exemplar flowchart is presented for aqueous workup of awkwardly hydrophilic products. Its use is illustrated with real synthetic compounds and model examples.
AB - Reaction workup can be a complex problem for those facing novel synthesis of difficult compounds for the first time. Workup problem solving by systematic thinking should be inculcated as mid-graduate-level is reached. A structured approach is proposed, building decision tree flowcharts to analyze challenges, and an exemplar flowchart is presented for aqueous workup of awkwardly hydrophilic products. Its use is illustrated with real synthetic compounds and model examples.
KW - Continuing Education
KW - Graduate Education/Research
KW - Inquiry Based/Discovery Learning
KW - Organic Chemistry
KW - Problem Solving/Decision Making
U2 - 10.1021/ed500580p
DO - 10.1021/ed500580p
M3 - Journal article
AN - SCOPUS:84924351876
VL - 92
SP - 488
EP - 496
JO - Journal of Chemical Education
JF - Journal of Chemical Education
SN - 0021-9584
IS - 3
ER -