Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
}
TY - JOUR
T1 - Recovery of erythromycin from aqueous solutions with an ionic liquid and high-pressure carbon dioxide
AU - Manic, Marina S.
AU - da Ponte, Manuel Nunes
AU - Najdanovic, Vesna
PY - 2011/7/15
Y1 - 2011/7/15
N2 - Recovery of erythromycin from aqueous solutions was studied in two steps: (i) single- and multi-stage extraction of erythromycin from an aqueous solution with a hydrophobic ionic liquid, 1-butyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imide [BMPyrrol][Tf(2)N], as a function of pH and feed to solvent volume ratio, and (ii) high-pressure CO(2) extraction of erythromycin from the ionic liquid, as a function of pressure, temperature and presence of water. Furthermore, data on the mutual solubilities of the hydrophobic ionic liquid and water, as well as on the solubility of erythromycin in [BMPyrrol][Tf(2)N], were obtained. The chemical stability of erythromycin in water-free and water saturated ionic liquid was tested.These results allowed the evaluation of the coupling of liquid-liquid and high-pressure CO(2) extractions. (C) 2011 Elsevier B.V. All rights reserved.
AB - Recovery of erythromycin from aqueous solutions was studied in two steps: (i) single- and multi-stage extraction of erythromycin from an aqueous solution with a hydrophobic ionic liquid, 1-butyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imide [BMPyrrol][Tf(2)N], as a function of pH and feed to solvent volume ratio, and (ii) high-pressure CO(2) extraction of erythromycin from the ionic liquid, as a function of pressure, temperature and presence of water. Furthermore, data on the mutual solubilities of the hydrophobic ionic liquid and water, as well as on the solubility of erythromycin in [BMPyrrol][Tf(2)N], were obtained. The chemical stability of erythromycin in water-free and water saturated ionic liquid was tested.These results allowed the evaluation of the coupling of liquid-liquid and high-pressure CO(2) extractions. (C) 2011 Elsevier B.V. All rights reserved.
KW - SOLVENTS
KW - Extraction
KW - AMINO-ACIDS
KW - SUPERCRITICAL CO2
KW - SOLUBILITY
KW - EXTRACTION
KW - Ionic liquids
KW - LIQUID/ORGANIC MIXTURES
KW - WATER
KW - SEPARATION
KW - 2-PHASE SYSTEM
KW - Supercritical CO(2)
KW - Antibiotic
KW - TEMPERATURE
U2 - 10.1016/j.cej.2011.04.037
DO - 10.1016/j.cej.2011.04.037
M3 - Journal article
VL - 171
SP - 904
EP - 911
JO - Chemical Engineering Journal
JF - Chemical Engineering Journal
SN - 1385-8947
IS - 3
ER -