Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Reverse spillover of avian viral vaccine strains from domesticated poultry to wild birds
AU - Rohaim, M. A.
AU - El Naggar, R. F.
AU - Helal, A. M.
AU - Hussein, H. A.
AU - Munir, Muhammad
N1 - Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.
PY - 2017/6/16
Y1 - 2017/6/16
N2 - Transmission of viruses from the commercial poultry to wild birds is an emerging paradigm of livestock-wildlife interface. Here, we report the identification and isolation of vaccine strains of avian paramyxovirus serotype 1 (APMV1) and avian coronaviruses (ACoV) from different wild bird species across eight Egyptian governorates between January 2014 and December 2015. Surveillance of avian respiratory viruses in free-ranging wild birds (n=297) identified three species that harboured or excreted APMV1 and ACoVs. Genetic characterization and phylogenetic analysis of recovered viruses revealed a close association with the most widely utilized vaccine strains in the country. These results highlight the potential spillover of vaccine-viruses probably due to extensive use of live-attenuated vaccines in the commercial poultry, and close interaction between domesticated and wild bird populations. Further exploring the full spectrum of vaccine-derived viral vaccine strains in wild birds might help to assess the emergence of future wild-birds origin viruses.
AB - Transmission of viruses from the commercial poultry to wild birds is an emerging paradigm of livestock-wildlife interface. Here, we report the identification and isolation of vaccine strains of avian paramyxovirus serotype 1 (APMV1) and avian coronaviruses (ACoV) from different wild bird species across eight Egyptian governorates between January 2014 and December 2015. Surveillance of avian respiratory viruses in free-ranging wild birds (n=297) identified three species that harboured or excreted APMV1 and ACoVs. Genetic characterization and phylogenetic analysis of recovered viruses revealed a close association with the most widely utilized vaccine strains in the country. These results highlight the potential spillover of vaccine-viruses probably due to extensive use of live-attenuated vaccines in the commercial poultry, and close interaction between domesticated and wild bird populations. Further exploring the full spectrum of vaccine-derived viral vaccine strains in wild birds might help to assess the emergence of future wild-birds origin viruses.
KW - Animals
KW - Animals, Wild
KW - Birds
KW - Egypt
KW - Gammacoronavirus
KW - Newcastle disease virus
KW - Phylogeny
KW - Poultry
KW - Poultry Diseases
KW - Vaccines, Attenuated
KW - Viral Vaccines
KW - Research Support, Non-U.S. Gov't
U2 - 10.1016/j.vaccine.2017.05.033
DO - 10.1016/j.vaccine.2017.05.033
M3 - Journal article
C2 - 28533052
VL - 35
SP - 3523
EP - 3527
JO - Vaccine
JF - Vaccine
SN - 0264-410X
IS - 28
ER -