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(S)- and (R)-5-Pyrrolidin-2-yl-1H-tetrazoles: Enantiomeric organocatalysts of broad utility in organic synthesis

Research output: Contribution to journalScientific review

Published

Journal publication date2007
JournalChimia
Journal number5
Volume61
Number of pages10
Pages247-256
Original languageEnglish

Abstract

This mini-review concerns the broad application of (S)- and (R)-5-pyrrolidin-2-yl-l H-tetrazoles as organocatalysts. A summary of methods for their synthesis is followed by a discussion of the general reaction mechanism and subsequent analysis of each reaction type for which they have proved to be efficient catalytic species. Where relevant, a comparison is made with other organocatalysts in similar asymmetric reaction processes.