Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Saccadic eye movements in essential blepharospasm
AU - Lueck, C. J.
AU - Tanyeri, S.
AU - Crawford, Trevor
AU - Elston, J. S.
AU - Kennard, C.
PY - 1990
Y1 - 1990
N2 - To provide evidence of an organic pathology for essential (idiopathic) blepharospasm, reflex saccadic eye movements in response to randomly stepped visual targets were assessed in seven affected patients and seven age-matched controls using the magnetic scleral search coil technique. The results indicate a significant prolongation in latency and a reduction in gain of horizontal saccades, and an increase in latency and reduction of peak velocity of large downward saccades. These findings suggest an organic component to the aetiology of blepharospasm, the pathology of which also appears to involve the oculomotor system. The pattern of the oculomotor disorder does not allow specific localisation but is consistent with the underlying pathology being localised in the basal ganglia.
AB - To provide evidence of an organic pathology for essential (idiopathic) blepharospasm, reflex saccadic eye movements in response to randomly stepped visual targets were assessed in seven affected patients and seven age-matched controls using the magnetic scleral search coil technique. The results indicate a significant prolongation in latency and a reduction in gain of horizontal saccades, and an increase in latency and reduction of peak velocity of large downward saccades. These findings suggest an organic component to the aetiology of blepharospasm, the pathology of which also appears to involve the oculomotor system. The pattern of the oculomotor disorder does not allow specific localisation but is consistent with the underlying pathology being localised in the basal ganglia.
KW - Saccades
KW - Essential blepharospasm
KW - Basal ganglia
U2 - 10.1007/BF00314623
DO - 10.1007/BF00314623
M3 - Journal article
C2 - 2391543
VL - 237
SP - 226
EP - 229
JO - Journal of Neurology
JF - Journal of Neurology
SN - 0340-5354
IS - 4
ER -