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Sedation effects on responsiveness : evaluating the reduction of antipsychotic medication in people with intellectual disability using a conditional probability approach.

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Published

Standard

Sedation effects on responsiveness : evaluating the reduction of antipsychotic medication in people with intellectual disability using a conditional probability approach. / Smith, C.; Felce, David; Ahmed, Z. et al.
In: Journal of Intellectual Disability Research, Vol. 46, No. 6, 09.2002, p. 464-471.

Research output: Contribution to Journal/MagazineJournal articlepeer-review

Harvard

Smith, C, Felce, D, Ahmed, Z, Fraser, WI, Kerr, M, Kiernan, C, Emerson, E, Robertson, J, Allen, D, Baxter, H & Thomas, J 2002, 'Sedation effects on responsiveness : evaluating the reduction of antipsychotic medication in people with intellectual disability using a conditional probability approach.', Journal of Intellectual Disability Research, vol. 46, no. 6, pp. 464-471. https://doi.org/10.1046/j.1365-2788.2002.00416.x

APA

Smith, C., Felce, D., Ahmed, Z., Fraser, W. I., Kerr, M., Kiernan, C., Emerson, E., Robertson, J., Allen, D., Baxter, H., & Thomas, J. (2002). Sedation effects on responsiveness : evaluating the reduction of antipsychotic medication in people with intellectual disability using a conditional probability approach. Journal of Intellectual Disability Research, 46(6), 464-471. https://doi.org/10.1046/j.1365-2788.2002.00416.x

Vancouver

Smith C, Felce D, Ahmed Z, Fraser WI, Kerr M, Kiernan C et al. Sedation effects on responsiveness : evaluating the reduction of antipsychotic medication in people with intellectual disability using a conditional probability approach. Journal of Intellectual Disability Research. 2002 Sept;46(6):464-471. doi: 10.1046/j.1365-2788.2002.00416.x

Author

Smith, C. ; Felce, David ; Ahmed, Z. et al. / Sedation effects on responsiveness : evaluating the reduction of antipsychotic medication in people with intellectual disability using a conditional probability approach. In: Journal of Intellectual Disability Research. 2002 ; Vol. 46, No. 6. pp. 464-471.

Bibtex

@article{34da1cbdd5da40008930e51bee07f4ae,
title = "Sedation effects on responsiveness : evaluating the reduction of antipsychotic medication in people with intellectual disability using a conditional probability approach.",
abstract = "The impact of the withdrawal of long-term antipsychotic medication prescribed to adults with intellectual disabilities on behavioural functioning has been investigated using a real-time direct observation methodology. Previous authors have reported a significant post-reduction difference in engagement in activity between the successful drug reduction and control groups. Method In the present study, sequential analysis of the relationship between staff:resident interaction and behavioural engagement was used to give a more precise measure of the extent to which user responsiveness is affected by drug withdrawal. Responsiveness was measured by calculating the likelihood of engagement occurring given the occurrence of staff interaction. This likelihood was represented by the statistic Yule's Q-value. Results High Yule's Q-value results pre- and post-baseline were found, indicating that clients were highly responsive to staff interaction. However, Yule's Q-value did not significantly increase following drug withdrawal. Conclusion The present study provides no evidence of greater responsiveness following the withdrawal of psychotropic medication.",
keywords = "responsiveness • psychotropic medication",
author = "C. Smith and David Felce and Z. Ahmed and Fraser, {W. I.} and M. Kerr and C. Kiernan and Eric Emerson and Janet Robertson and D. Allen and H. Baxter and J. Thomas",
year = "2002",
month = sep,
doi = "10.1046/j.1365-2788.2002.00416.x",
language = "English",
volume = "46",
pages = "464--471",
journal = "Journal of Intellectual Disability Research",
issn = "0964-2633",
publisher = "Blackwell Publishing Ltd",
number = "6",

}

RIS

TY - JOUR

T1 - Sedation effects on responsiveness : evaluating the reduction of antipsychotic medication in people with intellectual disability using a conditional probability approach.

AU - Smith, C.

AU - Felce, David

AU - Ahmed, Z.

AU - Fraser, W. I.

AU - Kerr, M.

AU - Kiernan, C.

AU - Emerson, Eric

AU - Robertson, Janet

AU - Allen, D.

AU - Baxter, H.

AU - Thomas, J.

PY - 2002/9

Y1 - 2002/9

N2 - The impact of the withdrawal of long-term antipsychotic medication prescribed to adults with intellectual disabilities on behavioural functioning has been investigated using a real-time direct observation methodology. Previous authors have reported a significant post-reduction difference in engagement in activity between the successful drug reduction and control groups. Method In the present study, sequential analysis of the relationship between staff:resident interaction and behavioural engagement was used to give a more precise measure of the extent to which user responsiveness is affected by drug withdrawal. Responsiveness was measured by calculating the likelihood of engagement occurring given the occurrence of staff interaction. This likelihood was represented by the statistic Yule's Q-value. Results High Yule's Q-value results pre- and post-baseline were found, indicating that clients were highly responsive to staff interaction. However, Yule's Q-value did not significantly increase following drug withdrawal. Conclusion The present study provides no evidence of greater responsiveness following the withdrawal of psychotropic medication.

AB - The impact of the withdrawal of long-term antipsychotic medication prescribed to adults with intellectual disabilities on behavioural functioning has been investigated using a real-time direct observation methodology. Previous authors have reported a significant post-reduction difference in engagement in activity between the successful drug reduction and control groups. Method In the present study, sequential analysis of the relationship between staff:resident interaction and behavioural engagement was used to give a more precise measure of the extent to which user responsiveness is affected by drug withdrawal. Responsiveness was measured by calculating the likelihood of engagement occurring given the occurrence of staff interaction. This likelihood was represented by the statistic Yule's Q-value. Results High Yule's Q-value results pre- and post-baseline were found, indicating that clients were highly responsive to staff interaction. However, Yule's Q-value did not significantly increase following drug withdrawal. Conclusion The present study provides no evidence of greater responsiveness following the withdrawal of psychotropic medication.

KW - responsiveness • psychotropic medication

U2 - 10.1046/j.1365-2788.2002.00416.x

DO - 10.1046/j.1365-2788.2002.00416.x

M3 - Journal article

VL - 46

SP - 464

EP - 471

JO - Journal of Intellectual Disability Research

JF - Journal of Intellectual Disability Research

SN - 0964-2633

IS - 6

ER -