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Short and medium chain length chlorinated paraffins in UK human milk fat

Research output: Contribution to Journal/Magazine › Journal article › peer-review

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Short and medium chain length chlorinated paraffins in UK human milk fat. / Thomas, Gareth O.; Farrar, David; Braekvelt, Eric et al.
In: Environment International, Vol. 32, No. 1, 01.2006, p. 34-40.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Thomas, GO, Farrar, D, Braekvelt, E, Stern, G, Kalantzi, OL, Martin, FL & Jones, KC 2006, 'Short and medium chain length chlorinated paraffins in UK human milk fat', Environment International, vol. 32, no. 1, pp. 34-40. https://doi.org/10.1016/j.envint.2005.04.006

APA

Thomas, G. O., Farrar, D., Braekvelt, E., Stern, G., Kalantzi, O. L., Martin, F. L., & Jones, K. C. (2006). Short and medium chain length chlorinated paraffins in UK human milk fat. Environment International, 32(1), 34-40. https://doi.org/10.1016/j.envint.2005.04.006

Vancouver

Thomas GO, Farrar D, Braekvelt E, Stern G, Kalantzi OL, Martin FL et al. Short and medium chain length chlorinated paraffins in UK human milk fat. Environment International. 2006 Jan;32(1):34-40. doi: 10.1016/j.envint.2005.04.006

Author

Thomas, Gareth O. ; Farrar, David ; Braekvelt, Eric et al. / Short and medium chain length chlorinated paraffins in UK human milk fat. In: Environment International. 2006 ; Vol. 32, No. 1. pp. 34-40.

Bibtex

@article{2aab2ba3e123469da2a2a00c9d988465,
title = "Short and medium chain length chlorinated paraffins in UK human milk fat",
abstract = "Chlorinated paraffins (also called polychlorinated n-alkanes — PCAs) are a class of industrial chemicals comprising chlorinated straight chain hydrocarbons. They have a wide range of applications and are now found in a range of environmental compartments. We analysed a total of 25 human milk-fat samples, donated by 18 individuals from the urban London and more rural Lancaster areas in the UK, for short chain PCAs (C10–C13 sPCAs) and medium chain PCAs (C14–C17 mPCAs), using gas chromatography–ECNI high-resolution mass spectrometry. Our study confirms that trace quantities of PCAs can reach human milk-fat. sPCAs were detected in all but four samples, while mPCAs were detected in all samples. The median sPCA concentration was 180 ng/g fat (range of 49 to 820 ng/g fat — detected values only) and the median mPCA concentration was 21 ng/g fat (range of 6.2 to 320 ng/g fat). No differences were noted in ranges of observed values for either sPCAs or mPCAs between samples from London and Lancaster. Most samples also exhibited similar patterns of sPCAs and mPCAs. One sample exhibited a different pattern for sPCAs and mPCAs, an observation that may be related to differences in exposure or biological factors for this individual.",
keywords = "Breast-milk, Organochlorine, SCCP, MCCP",
author = "Thomas, {Gareth O.} and David Farrar and Eric Braekvelt and Gary Stern and Kalantzi, {Olga L.} and Martin, {Francis L.} and Jones, {Kevin C.}",
year = "2006",
month = jan,
doi = "10.1016/j.envint.2005.04.006",
language = "English",
volume = "32",
pages = "34--40",
journal = "Environment International",
issn = "0160-4120",
publisher = "Elsevier Ltd",
number = "1",

}

RIS

TY - JOUR

T1 - Short and medium chain length chlorinated paraffins in UK human milk fat

AU - Thomas, Gareth O.

AU - Farrar, David

AU - Braekvelt, Eric

AU - Stern, Gary

AU - Kalantzi, Olga L.

AU - Martin, Francis L.

AU - Jones, Kevin C.

PY - 2006/1

Y1 - 2006/1

N2 - Chlorinated paraffins (also called polychlorinated n-alkanes — PCAs) are a class of industrial chemicals comprising chlorinated straight chain hydrocarbons. They have a wide range of applications and are now found in a range of environmental compartments. We analysed a total of 25 human milk-fat samples, donated by 18 individuals from the urban London and more rural Lancaster areas in the UK, for short chain PCAs (C10–C13 sPCAs) and medium chain PCAs (C14–C17 mPCAs), using gas chromatography–ECNI high-resolution mass spectrometry. Our study confirms that trace quantities of PCAs can reach human milk-fat. sPCAs were detected in all but four samples, while mPCAs were detected in all samples. The median sPCA concentration was 180 ng/g fat (range of 49 to 820 ng/g fat — detected values only) and the median mPCA concentration was 21 ng/g fat (range of 6.2 to 320 ng/g fat). No differences were noted in ranges of observed values for either sPCAs or mPCAs between samples from London and Lancaster. Most samples also exhibited similar patterns of sPCAs and mPCAs. One sample exhibited a different pattern for sPCAs and mPCAs, an observation that may be related to differences in exposure or biological factors for this individual.

AB - Chlorinated paraffins (also called polychlorinated n-alkanes — PCAs) are a class of industrial chemicals comprising chlorinated straight chain hydrocarbons. They have a wide range of applications and are now found in a range of environmental compartments. We analysed a total of 25 human milk-fat samples, donated by 18 individuals from the urban London and more rural Lancaster areas in the UK, for short chain PCAs (C10–C13 sPCAs) and medium chain PCAs (C14–C17 mPCAs), using gas chromatography–ECNI high-resolution mass spectrometry. Our study confirms that trace quantities of PCAs can reach human milk-fat. sPCAs were detected in all but four samples, while mPCAs were detected in all samples. The median sPCA concentration was 180 ng/g fat (range of 49 to 820 ng/g fat — detected values only) and the median mPCA concentration was 21 ng/g fat (range of 6.2 to 320 ng/g fat). No differences were noted in ranges of observed values for either sPCAs or mPCAs between samples from London and Lancaster. Most samples also exhibited similar patterns of sPCAs and mPCAs. One sample exhibited a different pattern for sPCAs and mPCAs, an observation that may be related to differences in exposure or biological factors for this individual.

KW - Breast-milk

KW - Organochlorine

KW - SCCP

KW - MCCP

U2 - 10.1016/j.envint.2005.04.006

DO - 10.1016/j.envint.2005.04.006

M3 - Journal article

VL - 32

SP - 34

EP - 40

JO - Environment International

JF - Environment International

SN - 0160-4120

IS - 1

ER -