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Signs of increased cortical hyperexcitability selectively associated with spontaneous anomalous bodily experiences in a nonclinical population

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Signs of increased cortical hyperexcitability selectively associated with spontaneous anomalous bodily experiences in a nonclinical population. / Braithwaite, Jason J; Broglia, Emma; Brincat, Oliver et al.
In: Cognitive Neuropsychiatry, Vol. 18, No. 6, 2013, p. 549-573.

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Braithwaite JJ, Broglia E, Brincat O, Stapley L, Wilkins AJ, Takahashi C. Signs of increased cortical hyperexcitability selectively associated with spontaneous anomalous bodily experiences in a nonclinical population. Cognitive Neuropsychiatry. 2013;18(6):549-573. doi: 10.1080/13546805.2013.768176

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Braithwaite, Jason J ; Broglia, Emma ; Brincat, Oliver et al. / Signs of increased cortical hyperexcitability selectively associated with spontaneous anomalous bodily experiences in a nonclinical population. In: Cognitive Neuropsychiatry. 2013 ; Vol. 18, No. 6. pp. 549-573.

Bibtex

@article{b08d47639b134e8e8bdd5c382f7b61a6,
title = "Signs of increased cortical hyperexcitability selectively associated with spontaneous anomalous bodily experiences in a nonclinical population",
abstract = "Introduction.The current study examined the presence of cortical hyperexcitability, in nonclinical hallucinators, reporting different forms of anomalous bodily experiences (ABEs). Groups reporting visual out-of-body experiences and nonvisual sensed-presence experiences were examined. It was hypothesised that only those hallucinators whose experiences contained visual elements would show increased signs of visual cortical hyperexcitability.Methods.One hundred and eighty-two participants completed the “Pattern-glare task” (involving the viewing of striped gratings with spatial frequencies irritable to visual cortex)—a task known to reflect degrees of cortical hyperexcitability associated with hallucinatory/aura experiences in neurological samples. Participants also completed questionnaire measures of anomalous “temporal-lobe experience” and predisposition to anomalous visual experiences.Results.Those reporting increased levels of anomalous bodily experiences provided significantly elevated scores on measures of temporal-lobe experience. Only the visual OBE group reported significantly elevated levels of cortical hyperexcitability as assessed by the pattern-glare task.Conclusions.Collectively, the results are consistent with there being an increased degree of background cortical hyperexcitability in the cortices of individuals predisposed to some ABE-type hallucinations, even in the nonclinical population. The present study also establishes the clinical utility of the pattern-glare task for examining signs of aberrant visual connectivity in relation to visual hallucinations.",
keywords = "Anomalous body experiences, Cortical hyperexcitability, Embodiment, Hallucinations",
author = "Braithwaite, {Jason J} and Emma Broglia and Oliver Brincat and Louise Stapley and Wilkins, {Arnold J.} and Chie Takahashi",
year = "2013",
doi = "10.1080/13546805.2013.768176",
language = "English",
volume = "18",
pages = "549--573",
journal = "Cognitive Neuropsychiatry",
issn = "1354-6805",
publisher = "Routledge",
number = "6",

}

RIS

TY - JOUR

T1 - Signs of increased cortical hyperexcitability selectively associated with spontaneous anomalous bodily experiences in a nonclinical population

AU - Braithwaite, Jason J

AU - Broglia, Emma

AU - Brincat, Oliver

AU - Stapley, Louise

AU - Wilkins, Arnold J.

AU - Takahashi, Chie

PY - 2013

Y1 - 2013

N2 - Introduction.The current study examined the presence of cortical hyperexcitability, in nonclinical hallucinators, reporting different forms of anomalous bodily experiences (ABEs). Groups reporting visual out-of-body experiences and nonvisual sensed-presence experiences were examined. It was hypothesised that only those hallucinators whose experiences contained visual elements would show increased signs of visual cortical hyperexcitability.Methods.One hundred and eighty-two participants completed the “Pattern-glare task” (involving the viewing of striped gratings with spatial frequencies irritable to visual cortex)—a task known to reflect degrees of cortical hyperexcitability associated with hallucinatory/aura experiences in neurological samples. Participants also completed questionnaire measures of anomalous “temporal-lobe experience” and predisposition to anomalous visual experiences.Results.Those reporting increased levels of anomalous bodily experiences provided significantly elevated scores on measures of temporal-lobe experience. Only the visual OBE group reported significantly elevated levels of cortical hyperexcitability as assessed by the pattern-glare task.Conclusions.Collectively, the results are consistent with there being an increased degree of background cortical hyperexcitability in the cortices of individuals predisposed to some ABE-type hallucinations, even in the nonclinical population. The present study also establishes the clinical utility of the pattern-glare task for examining signs of aberrant visual connectivity in relation to visual hallucinations.

AB - Introduction.The current study examined the presence of cortical hyperexcitability, in nonclinical hallucinators, reporting different forms of anomalous bodily experiences (ABEs). Groups reporting visual out-of-body experiences and nonvisual sensed-presence experiences were examined. It was hypothesised that only those hallucinators whose experiences contained visual elements would show increased signs of visual cortical hyperexcitability.Methods.One hundred and eighty-two participants completed the “Pattern-glare task” (involving the viewing of striped gratings with spatial frequencies irritable to visual cortex)—a task known to reflect degrees of cortical hyperexcitability associated with hallucinatory/aura experiences in neurological samples. Participants also completed questionnaire measures of anomalous “temporal-lobe experience” and predisposition to anomalous visual experiences.Results.Those reporting increased levels of anomalous bodily experiences provided significantly elevated scores on measures of temporal-lobe experience. Only the visual OBE group reported significantly elevated levels of cortical hyperexcitability as assessed by the pattern-glare task.Conclusions.Collectively, the results are consistent with there being an increased degree of background cortical hyperexcitability in the cortices of individuals predisposed to some ABE-type hallucinations, even in the nonclinical population. The present study also establishes the clinical utility of the pattern-glare task for examining signs of aberrant visual connectivity in relation to visual hallucinations.

KW - Anomalous body experiences

KW - Cortical hyperexcitability

KW - Embodiment

KW - Hallucinations

U2 - 10.1080/13546805.2013.768176

DO - 10.1080/13546805.2013.768176

M3 - Journal article

VL - 18

SP - 549

EP - 573

JO - Cognitive Neuropsychiatry

JF - Cognitive Neuropsychiatry

SN - 1354-6805

IS - 6

ER -