Final published version
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
}
TY - JOUR
T1 - Structural and in vitro adhesion analysis of a novel covalently coupled bioactive composite
AU - Khan, A.S.
AU - Hassan, K.R.
AU - Bukhari, S.F.
AU - Wong, F.S.L.
AU - Rehman, I.U.
PY - 2012
Y1 - 2012
N2 - The interfacial adhesion between a restorative composite and tooth is one of the major factors that determine the ultimate performance of composite restoration. A novel polyurethane (PU) composite material was prepared by chemically binding the nano-hydroxyapatite (nHA) to the diisocyanate component in the PU backbone by utilizing solvent polymerization. The procedure involved stepwise addition of monomeric units of the PU and optimizing the reagent concentrations. The resultant materials were characterized structurally (Raman Spectroscopy) and in vitro bioactive analysis was conducted in modified-simulated body fluid for periodical time intervals. The in vitro study evaluated the push-out bond strength of existing obturating material and novel covalently linked PU/nHA composites to dentin after long-term storage in deionized water and artificial saliva. Human extracted molar roots were filled with experimental samples and analyzed at predetermined time intervals. The shear bond strength of samples was measured and surface morphologies were evaluated. Covalent bond formation was achieved between PU and nHA without intermediate coupling agent. With the increase in concentration of nHA, the composite showed more bioactivity and adhesion toward tooth structure. Bond strength of this new composite were in accordance with obutrating material, therefore, the material can be used as an obturating material because of its direct adhesion with tooth structure. © 2011 Wiley Periodicals, Inc.
AB - The interfacial adhesion between a restorative composite and tooth is one of the major factors that determine the ultimate performance of composite restoration. A novel polyurethane (PU) composite material was prepared by chemically binding the nano-hydroxyapatite (nHA) to the diisocyanate component in the PU backbone by utilizing solvent polymerization. The procedure involved stepwise addition of monomeric units of the PU and optimizing the reagent concentrations. The resultant materials were characterized structurally (Raman Spectroscopy) and in vitro bioactive analysis was conducted in modified-simulated body fluid for periodical time intervals. The in vitro study evaluated the push-out bond strength of existing obturating material and novel covalently linked PU/nHA composites to dentin after long-term storage in deionized water and artificial saliva. Human extracted molar roots were filled with experimental samples and analyzed at predetermined time intervals. The shear bond strength of samples was measured and surface morphologies were evaluated. Covalent bond formation was achieved between PU and nHA without intermediate coupling agent. With the increase in concentration of nHA, the composite showed more bioactivity and adhesion toward tooth structure. Bond strength of this new composite were in accordance with obutrating material, therefore, the material can be used as an obturating material because of its direct adhesion with tooth structure. © 2011 Wiley Periodicals, Inc.
KW - bioactivity
KW - nano-hydroxyapatite
KW - polyurethane
KW - Raman spectroscopy
KW - tooth adhesion
KW - Adhesion analysis
KW - Artificial saliva
KW - Bioactive composites
KW - Composite restorations
KW - Covalent bond formation
KW - Diisocyanates
KW - In-vitro
KW - Interfacial adhesions
KW - Intermediate coupling
KW - Long-term storage
KW - Major factors
KW - Monomeric units
KW - Nano-hydroxyapatite
KW - Polyurethane composites
KW - Push-out
KW - Reagent concentration
KW - Restorative composites
KW - Shear bond strengths
KW - Time interval
KW - Tooth structure
KW - Adhesion
KW - Apatite
KW - Bioactivity
KW - Body fluids
KW - Composite materials
KW - Coupling agents
KW - Deionized water
KW - Hydroxyapatite
KW - Nanocomposites
KW - Polyurethanes
KW - Raman scattering
KW - Bond strength (materials)
KW - hydroxyapatite
KW - nanocomposite
KW - polyurethan
KW - saliva substitute
KW - article
KW - body fluid
KW - cell culture
KW - chemical binding
KW - composite material
KW - dentin
KW - in vitro study
KW - microbial adhesion
KW - molar tooth
KW - nonhuman
KW - polymerization
KW - Raman spectrometry
KW - scanning electron microscopy
KW - thermal analysis
KW - tooth
KW - tooth extraction
KW - Adhesiveness
KW - Body Fluids
KW - Composite Resins
KW - Dentin
KW - Durapatite
KW - Humans
KW - Materials Testing
KW - Molar
KW - Shear Strength
KW - Spectrum Analysis, Raman
KW - Tooth Root
U2 - 10.1002/jbm.b.31945
DO - 10.1002/jbm.b.31945
M3 - Journal article
VL - 100 B
SP - 239
EP - 248
JO - Journal of Biomedical Materials Research Part B: Applied Biomaterials
JF - Journal of Biomedical Materials Research Part B: Applied Biomaterials
SN - 1552-4973
IS - 1
ER -