Final published version
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
}
TY - JOUR
T1 - Structural evaluation of human and sheep bone and comparison with synthetic hydroxyapatite by FT‐Raman spectroscopy
AU - Rehman, I.
AU - Smith, R.
AU - Hench, L.L.
AU - Bonfield, W.
PY - 1995/10/1
Y1 - 1995/10/1
N2 - The composition of whole human and sheep cortical bone tissue, and of a synthetic hydroxyapatite (P120), were compared using Fourier transform Raman (FT‐Raman) spectroscopy. Deproteination procedures to remove the bulk of the collagen present in bone tissue allowed isolation of the mineral phase. A comparison of the spectra obtained from both whole and deproteinated bone with those of synthetic hydroxyapatite showed direct correlation only in the region of 952 cm−1 (symmetric PO mode). In contrast, human and sheep bone were very closely matched in both, the organic and inorganic structures. The results demonstrate that deproteination of bone is not a necessary precursor to obtain spectral information. © 1995 John Wiley & Sons, Inc. Copyright © 1995 John Wiley & Sons, Inc.
AB - The composition of whole human and sheep cortical bone tissue, and of a synthetic hydroxyapatite (P120), were compared using Fourier transform Raman (FT‐Raman) spectroscopy. Deproteination procedures to remove the bulk of the collagen present in bone tissue allowed isolation of the mineral phase. A comparison of the spectra obtained from both whole and deproteinated bone with those of synthetic hydroxyapatite showed direct correlation only in the region of 952 cm−1 (symmetric PO mode). In contrast, human and sheep bone were very closely matched in both, the organic and inorganic structures. The results demonstrate that deproteination of bone is not a necessary precursor to obtain spectral information. © 1995 John Wiley & Sons, Inc. Copyright © 1995 John Wiley & Sons, Inc.
KW - Biomaterials
KW - Bone
KW - Collagen
KW - Composition
KW - Evaluation
KW - Medical applications
KW - Molecular structure
KW - Nondestructive examination
KW - Physiology
KW - Raman spectroscopy
KW - Calcium phosphate
KW - Deproteination
KW - Fourier transform-Raman spectroscopy
KW - Synthetic hydroxyapatite
KW - Calcium compounds
KW - hydroxyapatite
KW - animal tissue
KW - article
KW - bone mineral
KW - bone structure
KW - cortical bone
KW - Fourier transformation
KW - human
KW - human tissue
KW - Raman spectrometry
KW - sheep
KW - Animal
KW - Bone and Bones
KW - Bone Demineralization Technique
KW - Calcium
KW - Calcium Phosphates
KW - Comparative Study
KW - Fourier Analysis
KW - Human
KW - Hydroxyapatites
KW - Male
KW - Middle Age
KW - Sheep
KW - Spectrum Analysis, Raman
KW - Support, Non-U.S. Gov't
U2 - 10.1002/jbm.820291016
DO - 10.1002/jbm.820291016
M3 - Journal article
VL - 29
SP - 1287
EP - 1294
JO - Journal of Biomedical Materials Research Part A
JF - Journal of Biomedical Materials Research Part A
SN - 0021-9304
IS - 10
ER -