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Supercontinuum ultra-high resolution line-field OCT: Experimental spectrograph comparison and comparison with current clinical OCT systems by the imaging of a human cornea

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  • Samuel Lawman
  • Vito Romano
  • Peter W. Madden
  • Sharon Mason
  • Bryan M. Williams
  • Yalin Zheng
  • Yao Chun Shen
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Abstract

Ultra high axial resolution (UHR) was demonstrated early in the development of optical coherence tomography (OCT), but has not yet reached clinical practice. We present the combination of supercontinuum light source and line field (LF-) OCT as a technical and economical route to get UHR-OCT into clinic and oer OCT application areas. We directly compare images of a human donor cornea taken with low and high resolution current generation clinical OCT systems with UHR-LF-OCT. These images highlight the massive information increase of UHR-OCT. Application to pharmaceutical pellets, and the functionality and imaging performance of different imaging spectrograph choices for LF- OCT are also demonstrated.