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Sutureless amniotic membrane transplantation for ocular surface reconstruction with a chemically defined bioadhesive

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Sutureless amniotic membrane transplantation for ocular surface reconstruction with a chemically defined bioadhesive. / Takaoka, Maho; Nakamura, Takahiro; Sugai, Hajime et al.
In: Biomaterials, Vol. 29, No. 19, 07.2008, p. 2923-2931.

Research output: Contribution to Journal/MagazineJournal articlepeer-review

Harvard

Takaoka, M, Nakamura, T, Sugai, H, Bentley, AJ, Nakajima, N, Fullwood, NJ, Yokoi, N, Hyon, S-H & Kinoshita, S 2008, 'Sutureless amniotic membrane transplantation for ocular surface reconstruction with a chemically defined bioadhesive', Biomaterials, vol. 29, no. 19, pp. 2923-2931. https://doi.org/10.1016/j.biomaterials.2008.03.027

APA

Takaoka, M., Nakamura, T., Sugai, H., Bentley, A. J., Nakajima, N., Fullwood, N. J., Yokoi, N., Hyon, S-H., & Kinoshita, S. (2008). Sutureless amniotic membrane transplantation for ocular surface reconstruction with a chemically defined bioadhesive. Biomaterials, 29(19), 2923-2931. https://doi.org/10.1016/j.biomaterials.2008.03.027

Vancouver

Takaoka M, Nakamura T, Sugai H, Bentley AJ, Nakajima N, Fullwood NJ et al. Sutureless amniotic membrane transplantation for ocular surface reconstruction with a chemically defined bioadhesive. Biomaterials. 2008 Jul;29(19):2923-2931. doi: 10.1016/j.biomaterials.2008.03.027

Author

Takaoka, Maho ; Nakamura, Takahiro ; Sugai, Hajime et al. / Sutureless amniotic membrane transplantation for ocular surface reconstruction with a chemically defined bioadhesive. In: Biomaterials. 2008 ; Vol. 29, No. 19. pp. 2923-2931.

Bibtex

@article{1b639e60c1294a7e91e1a017c4ec3a52,
title = "Sutureless amniotic membrane transplantation for ocular surface reconstruction with a chemically defined bioadhesive",
abstract = "The purpose of this study was to evaluate the efficiency and safety of a sutureless amniotic membrane transplantation (AMT) for ocular surface reconstruction with a chemically defined bioadhesive (CDB). The CDB was synthesized from aldehyded polysaccharides and epsilon-poly(L-lysine), two kinds of medical and food additives, as starting materials. Biocompatibility assay indicated that the CDB showed excellent biocompatibility with in vitro and in vivo ocular surface tissues and most of the CDB was histologically degraded within 4 weeks. Sutureless AMT using the CDB was safely and successfully performed onto a rabbit scleral surface. Transplanted amniotic membrane (AM) evaluated by histological, electron microscopic- and immunohistochemical examination indicated that the CDB did not affect normal differentiation of the cells or the integrity of the surrounding tissue. Thus, this newly developed CDB was found to be very useful for sutureless AMT for ocular surface reconstruction, without considering the risk of infection. It has the ability to fix AM to the ocular surface for a long time-period without additional inflammation, scarring, or damage to the surrounding tissues. (C) 2008 Elsevier Ltd. All rights reserved.",
keywords = "ophthalmology, transplantation, sutureless, ocular surface, bioadhesive, biocompatibility, SEALING CORNEAL INCISIONS, STEM-CELL TRANSPLANTATION, PARVOVIRUS B19 INFECTION, STEVENS-JOHNSON-SYNDROME, LIMBAL EPITHELIAL-CELLS, TISSUE ADHESIVE, FIBRIN GLUE, AUTOLOGOUS TRANSPLANTATION, CONJUNCTIVAL AUTOGRAFTS, RECURRENT PTERYGIA",
author = "Maho Takaoka and Takahiro Nakamura and Hajime Sugai and Bentley, {Adam James} and Naoki Nakajima and Fullwood, {Nigel J.} and Norihiko Yokoi and Suong-Hyu Hyon and Shigeru Kinoshita",
year = "2008",
month = jul,
doi = "10.1016/j.biomaterials.2008.03.027",
language = "English",
volume = "29",
pages = "2923--2931",
journal = "Biomaterials",
issn = "0142-9612",
publisher = "PERGAMON-ELSEVIER SCIENCE LTD",
number = "19",

}

RIS

TY - JOUR

T1 - Sutureless amniotic membrane transplantation for ocular surface reconstruction with a chemically defined bioadhesive

AU - Takaoka, Maho

AU - Nakamura, Takahiro

AU - Sugai, Hajime

AU - Bentley, Adam James

AU - Nakajima, Naoki

AU - Fullwood, Nigel J.

AU - Yokoi, Norihiko

AU - Hyon, Suong-Hyu

AU - Kinoshita, Shigeru

PY - 2008/7

Y1 - 2008/7

N2 - The purpose of this study was to evaluate the efficiency and safety of a sutureless amniotic membrane transplantation (AMT) for ocular surface reconstruction with a chemically defined bioadhesive (CDB). The CDB was synthesized from aldehyded polysaccharides and epsilon-poly(L-lysine), two kinds of medical and food additives, as starting materials. Biocompatibility assay indicated that the CDB showed excellent biocompatibility with in vitro and in vivo ocular surface tissues and most of the CDB was histologically degraded within 4 weeks. Sutureless AMT using the CDB was safely and successfully performed onto a rabbit scleral surface. Transplanted amniotic membrane (AM) evaluated by histological, electron microscopic- and immunohistochemical examination indicated that the CDB did not affect normal differentiation of the cells or the integrity of the surrounding tissue. Thus, this newly developed CDB was found to be very useful for sutureless AMT for ocular surface reconstruction, without considering the risk of infection. It has the ability to fix AM to the ocular surface for a long time-period without additional inflammation, scarring, or damage to the surrounding tissues. (C) 2008 Elsevier Ltd. All rights reserved.

AB - The purpose of this study was to evaluate the efficiency and safety of a sutureless amniotic membrane transplantation (AMT) for ocular surface reconstruction with a chemically defined bioadhesive (CDB). The CDB was synthesized from aldehyded polysaccharides and epsilon-poly(L-lysine), two kinds of medical and food additives, as starting materials. Biocompatibility assay indicated that the CDB showed excellent biocompatibility with in vitro and in vivo ocular surface tissues and most of the CDB was histologically degraded within 4 weeks. Sutureless AMT using the CDB was safely and successfully performed onto a rabbit scleral surface. Transplanted amniotic membrane (AM) evaluated by histological, electron microscopic- and immunohistochemical examination indicated that the CDB did not affect normal differentiation of the cells or the integrity of the surrounding tissue. Thus, this newly developed CDB was found to be very useful for sutureless AMT for ocular surface reconstruction, without considering the risk of infection. It has the ability to fix AM to the ocular surface for a long time-period without additional inflammation, scarring, or damage to the surrounding tissues. (C) 2008 Elsevier Ltd. All rights reserved.

KW - ophthalmology

KW - transplantation

KW - sutureless

KW - ocular surface

KW - bioadhesive

KW - biocompatibility

KW - SEALING CORNEAL INCISIONS

KW - STEM-CELL TRANSPLANTATION

KW - PARVOVIRUS B19 INFECTION

KW - STEVENS-JOHNSON-SYNDROME

KW - LIMBAL EPITHELIAL-CELLS

KW - TISSUE ADHESIVE

KW - FIBRIN GLUE

KW - AUTOLOGOUS TRANSPLANTATION

KW - CONJUNCTIVAL AUTOGRAFTS

KW - RECURRENT PTERYGIA

U2 - 10.1016/j.biomaterials.2008.03.027

DO - 10.1016/j.biomaterials.2008.03.027

M3 - Journal article

VL - 29

SP - 2923

EP - 2931

JO - Biomaterials

JF - Biomaterials

SN - 0142-9612

IS - 19

ER -