Final published version
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Synthesis and characterization of a novel fast-set proline-derivative-containing glass ionomer cement with enhanced mechanical properties
AU - Moshaverinia, A.
AU - Roohpour, N.
AU - Rehman, I.U.
PY - 2009
Y1 - 2009
N2 - In this study, a methacryloyl derivative of l-proline was synthesized, characterized and incorporated into a conventional glass ionomer cement (GIC) with a polyacid composition. Subsequently, the effects of incorporation of synthesized N-methacryloyl-proline and terpolymer on the GIC's mechanical and working properties were studied. 1-Methacryloylpyrrolidone-2-carboxylic acid was synthesized and used in a polymerization reaction with acrylic acid and itaconic acid in order to form terpolymer which was used in Fuji II commercial GIC formulations. Chemical structural characterization of the resulting products was performed using 1H nuclear magnetic resonance and Fourier transform infrared spectroscopy. The viscosity and molecular weight of the terpolymer were also measured. The mechanical strength properties of the modified GICs were evaluated after 24 h or 1 week of immersion in distilled water at 37 °C. Analysis of variance was used to study the statistical significance of the mechanical strengths and working properties, and to compare them with a control group. Results showed that N-methacryloyl-proline modified GICs exhibited significantly higher compressive strength (CS; 195-210 MPa), higher diametral tensile strength (DTS; 19-26 MPa) and higher biaxial flexural strength (38-46 MPa) in comparison to Fuji II GIC (161-166 MPa in CS, 12-14 MPa in DTS and 13-18 MPa in biaxial flexural strength). The working properties (setting and working time) of the modified samples showed that the modified cement was a fast-set cement. It was concluded that a novel amino acid-containing GIC has been developed in this study with 27%, 94% and 170% increases in values for compressive, diametral tensile and biaxial flexural strength, respectively, in comparison to commercial Fuji II GIC. © 2008 Acta Materialia Inc.
AB - In this study, a methacryloyl derivative of l-proline was synthesized, characterized and incorporated into a conventional glass ionomer cement (GIC) with a polyacid composition. Subsequently, the effects of incorporation of synthesized N-methacryloyl-proline and terpolymer on the GIC's mechanical and working properties were studied. 1-Methacryloylpyrrolidone-2-carboxylic acid was synthesized and used in a polymerization reaction with acrylic acid and itaconic acid in order to form terpolymer which was used in Fuji II commercial GIC formulations. Chemical structural characterization of the resulting products was performed using 1H nuclear magnetic resonance and Fourier transform infrared spectroscopy. The viscosity and molecular weight of the terpolymer were also measured. The mechanical strength properties of the modified GICs were evaluated after 24 h or 1 week of immersion in distilled water at 37 °C. Analysis of variance was used to study the statistical significance of the mechanical strengths and working properties, and to compare them with a control group. Results showed that N-methacryloyl-proline modified GICs exhibited significantly higher compressive strength (CS; 195-210 MPa), higher diametral tensile strength (DTS; 19-26 MPa) and higher biaxial flexural strength (38-46 MPa) in comparison to Fuji II GIC (161-166 MPa in CS, 12-14 MPa in DTS and 13-18 MPa in biaxial flexural strength). The working properties (setting and working time) of the modified samples showed that the modified cement was a fast-set cement. It was concluded that a novel amino acid-containing GIC has been developed in this study with 27%, 94% and 170% increases in values for compressive, diametral tensile and biaxial flexural strength, respectively, in comparison to commercial Fuji II GIC. © 2008 Acta Materialia Inc.
KW - Glass ionomer cements
KW - Mechanical strength
KW - Polyacrylic acid
KW - Proline derivative
KW - Synthesis
KW - acrylic acid
KW - carboxylic acid derivative
KW - glass ionomer
KW - itaconic acid
KW - proline derivative
KW - article
KW - chemical composition
KW - chemical structure
KW - compressive strength
KW - controlled study
KW - infrared spectroscopy
KW - molecular weight
KW - polymerization
KW - priority journal
KW - proton nuclear magnetic resonance
KW - synthesis
KW - tensile strength
KW - viscosity
KW - Compressive Strength
KW - Glass Ionomer Cements
KW - Magnetic Resonance Spectroscopy
KW - Materials Testing
KW - Molecular Weight
KW - Polymers
KW - Pressure
KW - Proline
KW - Spectroscopy, Fourier Transform Infrared
KW - Stress, Mechanical
KW - Temperature
KW - Tensile Strength
KW - Time Factors
KW - Viscosity
KW - Water
U2 - 10.1016/j.actbio.2008.06.011
DO - 10.1016/j.actbio.2008.06.011
M3 - Journal article
VL - 5
SP - 498
EP - 507
JO - Acta Biomaterialia
JF - Acta Biomaterialia
SN - 1742-7061
IS - 1
ER -