Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Synthesis of medium-ring and iodinated biaryl compounds by organocuprate oxidation
AU - Surry, DS
AU - Su, XB
AU - Fox, DJ
AU - Franckevicius, Vilius
AU - Macdonald, SJF
AU - Spring, DR
PY - 2005/3/11
Y1 - 2005/3/11
N2 - A biaryl banquet! Biphenyls with four ortho substituents, heteroaromatic compounds, iodinated biaryls, and medium rings containing biaryls are all readily synthesized by organocuprate oxidation. The utility of this new methodology is illustrated by the efficient synthesis of the medium-ring core of sanguiin H-5 (see scheme).
AB - A biaryl banquet! Biphenyls with four ortho substituents, heteroaromatic compounds, iodinated biaryls, and medium rings containing biaryls are all readily synthesized by organocuprate oxidation. The utility of this new methodology is illustrated by the efficient synthesis of the medium-ring core of sanguiin H-5 (see scheme).
KW - organocuprates
KW - C-C coupling
KW - oxidation
KW - VINYL CHLORIDES
KW - TEMPLATE
KW - biaryls
KW - medium-ring compounds
KW - ULLMANN COUPLING REACTION
KW - ARYL BOND FORMATION
KW - 1ST SYNTHESIS
KW - FUNCTIONALIZED ARYLMAGNESIUM
KW - CONVENIENT
KW - SYMMETRICAL BIARYLS
KW - FACILE SYNTHESIS
KW - SALICYL ALCOHOL
U2 - 10.1002/anie.200462642
DO - 10.1002/anie.200462642
M3 - Journal article
VL - 44
SP - 1870
EP - 1873
JO - Angewandte Chemie International Edition
JF - Angewandte Chemie International Edition
SN - 1433-7851
IS - 12
ER -