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The action of a mast cell protease on the cuticular collagens of Necator americanus.

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The action of a mast cell protease on the cuticular collagens of Necator americanus. / McKean, Paul G.; Pritchard, D. I.

In: Parasite Immunology, Vol. 11, No. 3, 05.1989, p. 293-297.

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McKean, Paul G. ; Pritchard, D. I. / The action of a mast cell protease on the cuticular collagens of Necator americanus. In: Parasite Immunology. 1989 ; Vol. 11, No. 3. pp. 293-297.

Bibtex

@article{0d0f81ea5f2f4847a89ccd84825b9898,
title = "The action of a mast cell protease on the cuticular collagens of Necator americanus.",
abstract = "Collagen-like proteins, thought to be responsible for maintaining the structural integrity of the nematode cuticle, were isolated from adult Necator americanus and shown to be susceptible to digestion by purified mast cell proteases. Although these collagens would appear normally to be masked by superficially expressed (surface) antigens, it is suggested that a sufficiently avid and specific immune response could remove this potentially protective coat, rendering the structurally important underlying layers open to immune attack.",
author = "McKean, {Paul G.} and Pritchard, {D. I.}",
year = "1989",
month = may
doi = "10.1111/j.1365-3024.1989.tb00667.x",
language = "English",
volume = "11",
pages = "293--297",
journal = "Parasite Immunology",
issn = "0141-9838",
publisher = "Wiley-Blackwell",
number = "3",

}

RIS

TY - JOUR

T1 - The action of a mast cell protease on the cuticular collagens of Necator americanus.

AU - McKean, Paul G.

AU - Pritchard, D. I.

PY - 1989/5

Y1 - 1989/5

N2 - Collagen-like proteins, thought to be responsible for maintaining the structural integrity of the nematode cuticle, were isolated from adult Necator americanus and shown to be susceptible to digestion by purified mast cell proteases. Although these collagens would appear normally to be masked by superficially expressed (surface) antigens, it is suggested that a sufficiently avid and specific immune response could remove this potentially protective coat, rendering the structurally important underlying layers open to immune attack.

AB - Collagen-like proteins, thought to be responsible for maintaining the structural integrity of the nematode cuticle, were isolated from adult Necator americanus and shown to be susceptible to digestion by purified mast cell proteases. Although these collagens would appear normally to be masked by superficially expressed (surface) antigens, it is suggested that a sufficiently avid and specific immune response could remove this potentially protective coat, rendering the structurally important underlying layers open to immune attack.

U2 - 10.1111/j.1365-3024.1989.tb00667.x

DO - 10.1111/j.1365-3024.1989.tb00667.x

M3 - Journal article

VL - 11

SP - 293

EP - 297

JO - Parasite Immunology

JF - Parasite Immunology

SN - 0141-9838

IS - 3

ER -