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The common ancestor at a non-neutral locus.

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The common ancestor at a non-neutral locus. / Fearnhead, Paul.
In: Journal of Applied Probability, Vol. 39, No. 1, 2002, p. 38-54.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Fearnhead, P 2002, 'The common ancestor at a non-neutral locus.', Journal of Applied Probability, vol. 39, no. 1, pp. 38-54. https://doi.org/10.1239/jap/1019737986

APA

Fearnhead, P. (2002). The common ancestor at a non-neutral locus. Journal of Applied Probability, 39(1), 38-54. https://doi.org/10.1239/jap/1019737986

Vancouver

Fearnhead P. The common ancestor at a non-neutral locus. Journal of Applied Probability. 2002;39(1):38-54. doi: 10.1239/jap/1019737986

Author

Fearnhead, Paul. / The common ancestor at a non-neutral locus. In: Journal of Applied Probability. 2002 ; Vol. 39, No. 1. pp. 38-54.

Bibtex

@article{e56fcef30cad40029029e0e1e4c25023,
title = "The common ancestor at a non-neutral locus.",
abstract = "We consider a nonneutral population genetics model with parent-independent mutations and two selective classes. We calculate the stationary distribution of the type of the common ancestor of a sample of genes from this model. The expected fitness of any ancestor (including the most recent common ancestor of any sample) is shown to be greater than the expected fitness of a randomly chosen gene from the population. The process of mutations to the common ancestor is also analysed. Our results are related to, but more general than, results obtained from diffusion theory.",
keywords = "Ancestral selection graph, common ancestor, fitness, fixation, parent-independent mutations",
author = "Paul Fearnhead",
year = "2002",
doi = "10.1239/jap/1019737986",
language = "English",
volume = "39",
pages = "38--54",
journal = "Journal of Applied Probability",
publisher = "University of Sheffield",
number = "1",

}

RIS

TY - JOUR

T1 - The common ancestor at a non-neutral locus.

AU - Fearnhead, Paul

PY - 2002

Y1 - 2002

N2 - We consider a nonneutral population genetics model with parent-independent mutations and two selective classes. We calculate the stationary distribution of the type of the common ancestor of a sample of genes from this model. The expected fitness of any ancestor (including the most recent common ancestor of any sample) is shown to be greater than the expected fitness of a randomly chosen gene from the population. The process of mutations to the common ancestor is also analysed. Our results are related to, but more general than, results obtained from diffusion theory.

AB - We consider a nonneutral population genetics model with parent-independent mutations and two selective classes. We calculate the stationary distribution of the type of the common ancestor of a sample of genes from this model. The expected fitness of any ancestor (including the most recent common ancestor of any sample) is shown to be greater than the expected fitness of a randomly chosen gene from the population. The process of mutations to the common ancestor is also analysed. Our results are related to, but more general than, results obtained from diffusion theory.

KW - Ancestral selection graph

KW - common ancestor

KW - fitness

KW - fixation

KW - parent-independent mutations

U2 - 10.1239/jap/1019737986

DO - 10.1239/jap/1019737986

M3 - Journal article

VL - 39

SP - 38

EP - 54

JO - Journal of Applied Probability

JF - Journal of Applied Probability

IS - 1

ER -