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The importance of cellular localisation of probes: synthesis, photophysical properties, DNA interactions and cellular imaging properties of rhenium dppz complexes with known cellular localisation vectors.

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The importance of cellular localisation of probes: synthesis, photophysical properties, DNA interactions and cellular imaging properties of rhenium dppz complexes with known cellular localisation vectors. / Thorp-Greenwood, Flora L. ; Coogan, Michael; Mishra, Lallan et al.
In: New Journal of Chemistry, Vol. 36, No. 1, 2012, p. 64-72.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Thorp-Greenwood, FL, Coogan, M, Mishra, L, Kumari, N, Rai, G & Saripella, S 2012, 'The importance of cellular localisation of probes: synthesis, photophysical properties, DNA interactions and cellular imaging properties of rhenium dppz complexes with known cellular localisation vectors.', New Journal of Chemistry, vol. 36, no. 1, pp. 64-72. https://doi.org/10.1039/C1NJ20662A

APA

Thorp-Greenwood, F. L., Coogan, M., Mishra, L., Kumari, N., Rai, G., & Saripella, S. (2012). The importance of cellular localisation of probes: synthesis, photophysical properties, DNA interactions and cellular imaging properties of rhenium dppz complexes with known cellular localisation vectors. New Journal of Chemistry, 36(1), 64-72. https://doi.org/10.1039/C1NJ20662A

Vancouver

Thorp-Greenwood FL, Coogan M, Mishra L, Kumari N, Rai G, Saripella S. The importance of cellular localisation of probes: synthesis, photophysical properties, DNA interactions and cellular imaging properties of rhenium dppz complexes with known cellular localisation vectors. New Journal of Chemistry. 2012;36(1):64-72. doi: 10.1039/C1NJ20662A

Author

Thorp-Greenwood, Flora L. ; Coogan, Michael ; Mishra, Lallan et al. / The importance of cellular localisation of probes: synthesis, photophysical properties, DNA interactions and cellular imaging properties of rhenium dppz complexes with known cellular localisation vectors. In: New Journal of Chemistry. 2012 ; Vol. 36, No. 1. pp. 64-72.

Bibtex

@article{271d0427142e424ca6eb87fcf2d2bc64,
title = "The importance of cellular localisation of probes: synthesis, photophysical properties, DNA interactions and cellular imaging properties of rhenium dppz complexes with known cellular localisation vectors.",
abstract = "The synthesis, photophysical properties, DNA binding, DNA cleavage and cellular imaging behaviour of a range of complexes of the type [Re(CO)3(dppz)(PyR)]+ are reported, where PyR represents a range of substituted pyridines which have previously been studied for cellular localisation of related complexes. Confocal imaging experiments confirm that the complexes retain the variety of cellular localisation behaviour associated with the PyR units in other complexes, and suggest applications as probes for oligonucleotides in specific cellular compartments (e.g. mitochondrial DNA). This study illustrates the importance of considering cellular localisation as a prime consideration in the design of probes for in vivo application.",
author = "Thorp-Greenwood, {Flora L.} and Michael Coogan and Lallan Mishra and Niraj Kumari and Geeta Rai and Srikrishna Saripella",
year = "2012",
doi = "10.1039/C1NJ20662A",
language = "English",
volume = "36",
pages = "64--72",
journal = "New Journal of Chemistry",
issn = "1369-9261",
publisher = "Royal Society of Chemistry",
number = "1",

}

RIS

TY - JOUR

T1 - The importance of cellular localisation of probes: synthesis, photophysical properties, DNA interactions and cellular imaging properties of rhenium dppz complexes with known cellular localisation vectors.

AU - Thorp-Greenwood, Flora L.

AU - Coogan, Michael

AU - Mishra, Lallan

AU - Kumari, Niraj

AU - Rai, Geeta

AU - Saripella, Srikrishna

PY - 2012

Y1 - 2012

N2 - The synthesis, photophysical properties, DNA binding, DNA cleavage and cellular imaging behaviour of a range of complexes of the type [Re(CO)3(dppz)(PyR)]+ are reported, where PyR represents a range of substituted pyridines which have previously been studied for cellular localisation of related complexes. Confocal imaging experiments confirm that the complexes retain the variety of cellular localisation behaviour associated with the PyR units in other complexes, and suggest applications as probes for oligonucleotides in specific cellular compartments (e.g. mitochondrial DNA). This study illustrates the importance of considering cellular localisation as a prime consideration in the design of probes for in vivo application.

AB - The synthesis, photophysical properties, DNA binding, DNA cleavage and cellular imaging behaviour of a range of complexes of the type [Re(CO)3(dppz)(PyR)]+ are reported, where PyR represents a range of substituted pyridines which have previously been studied for cellular localisation of related complexes. Confocal imaging experiments confirm that the complexes retain the variety of cellular localisation behaviour associated with the PyR units in other complexes, and suggest applications as probes for oligonucleotides in specific cellular compartments (e.g. mitochondrial DNA). This study illustrates the importance of considering cellular localisation as a prime consideration in the design of probes for in vivo application.

UR - http://www.scopus.com/inward/record.url?scp=84255176356&partnerID=8YFLogxK

U2 - 10.1039/C1NJ20662A

DO - 10.1039/C1NJ20662A

M3 - Journal article

AN - SCOPUS:84255176356

VL - 36

SP - 64

EP - 72

JO - New Journal of Chemistry

JF - New Journal of Chemistry

SN - 1369-9261

IS - 1

ER -