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  • MOLSTRUC-D-18-03618R1 (1)

    Rights statement: This is the author’s version of a work that was accepted for publication in Journal of Molecular Structure. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Journal of Molecular Structure, 1187, 2019 DOI: 10.1016/j.molstruc.2019.03.034

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The mineralization effect on chitosan hydrogel structure containing collagen and alkaline phosphatase

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<mark>Journal publication date</mark>5/07/2019
<mark>Journal</mark>Journal of Molecular Structure
Volume1187
Number of pages12
Pages (from-to)86-97
Publication StatusPublished
Early online date15/03/19
<mark>Original language</mark>English

Abstract

Introducing collagen the basic ingredient of bone tissue into the structure of chitosan gels that are formed at physiological body temperature, aims to create so-called biomimetic structures, which are close in composition to the natural composition of bone tissue. The aim of this study was to determine the influence of mineralization on the structural properties of thermosensitive chitosan-collagen gels containing alkaline phosphatase (ALP) by SEM, XRD FTIR and XPS analyses, compared to the previously presented structure of chitosan-collagen gels before mineralization.

Bibliographic note

This is the author’s version of a work that was accepted for publication in Journal of Molecular Structure. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Journal of Molecular Structure, 1187, 2019 DOI: 10.1016/j.molstruc.2019.03.034