Home > Research > Publications & Outputs > Therapeutic potential of genipin in central neu...

Research

Electronic data

  • manuscript final version

    Rights statement: The final publication is available at Springer via http://dx.doi.org/10.1007/s40263-016-0369-9

    Accepted author manuscript, 508 KB, PDF document

    Available under license: CC BY-NC: Creative Commons Attribution-NonCommercial 4.0 International License

Links

Text available via DOI:

View graph of relations

Therapeutic potential of genipin in central neurodegenerative diseases

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Published

Standard

Therapeutic potential of genipin in central neurodegenerative diseases. / Li, Yanwei; Li, Lin; Holscher, Christian.
In: CNS Drugs, Vol. 30, No. 10, 10.2016, p. 889-897.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Li, Y, Li, L & Holscher, C 2016, 'Therapeutic potential of genipin in central neurodegenerative diseases', CNS Drugs, vol. 30, no. 10, pp. 889-897. https://doi.org/10.1007/s40263-016-0369-9

APA

Li, Y., Li, L., & Holscher, C. (2016). Therapeutic potential of genipin in central neurodegenerative diseases. CNS Drugs, 30(10), 889-897. https://doi.org/10.1007/s40263-016-0369-9

Vancouver

Li Y, Li L, Holscher C. Therapeutic potential of genipin in central neurodegenerative diseases. CNS Drugs. 2016 Oct;30(10):889-897. Epub 2016 Jul 9. doi: 10.1007/s40263-016-0369-9

Author

Li, Yanwei ; Li, Lin ; Holscher, Christian. / Therapeutic potential of genipin in central neurodegenerative diseases. In: CNS Drugs. 2016 ; Vol. 30, No. 10. pp. 889-897.

Bibtex

@article{5ca9d5e45d5c4b9c97dce52ca4d947af,
title = "Therapeutic potential of genipin in central neurodegenerative diseases",
abstract = "Central neurodegenerative diseases, such as Alzheimer{\textquoteright}s disease (AD) and Parkinson{\textquoteright}s disease (PD), are one of the biggest health problems worldwide. Currently, there is no cure for these diseases. The Gardenia jasminoides fruit is a common herbal medicine in traditional Chinese medicine (TCM), and a variety of preparations are used as treatments for central nervous system (CNS) diseases. Pharmacokinetic studies suggest genipin is one of the main effective ingredients of G. jasminoides fruit extract (GFE). Accumulated research data show that genipin possesses a range of key pharmacological properties, such as anti-inflammatory, neuroprotective, neurogenic, antidiabetic, and antidepressant effects. Thus, genipin shows therapeutic potential for central neurodegenerative diseases. We review the pharmacological actions of genipin for the treatment of neurodegenerative diseases of the CNS. We also describe the potential mechanisms underlying these effects.",
author = "Yanwei Li and Lin Li and Christian Holscher",
note = "The final publication is available at Springer via http://dx.doi.org/10.1007/s40263-016-0369-9",
year = "2016",
month = oct,
doi = "10.1007/s40263-016-0369-9",
language = "English",
volume = "30",
pages = "889--897",
journal = "CNS Drugs",
issn = "1172-7047",
publisher = "ADIS INT LTD",
number = "10",

}

RIS

TY - JOUR

T1 - Therapeutic potential of genipin in central neurodegenerative diseases

AU - Li, Yanwei

AU - Li, Lin

AU - Holscher, Christian

N1 - The final publication is available at Springer via http://dx.doi.org/10.1007/s40263-016-0369-9

PY - 2016/10

Y1 - 2016/10

N2 - Central neurodegenerative diseases, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), are one of the biggest health problems worldwide. Currently, there is no cure for these diseases. The Gardenia jasminoides fruit is a common herbal medicine in traditional Chinese medicine (TCM), and a variety of preparations are used as treatments for central nervous system (CNS) diseases. Pharmacokinetic studies suggest genipin is one of the main effective ingredients of G. jasminoides fruit extract (GFE). Accumulated research data show that genipin possesses a range of key pharmacological properties, such as anti-inflammatory, neuroprotective, neurogenic, antidiabetic, and antidepressant effects. Thus, genipin shows therapeutic potential for central neurodegenerative diseases. We review the pharmacological actions of genipin for the treatment of neurodegenerative diseases of the CNS. We also describe the potential mechanisms underlying these effects.

AB - Central neurodegenerative diseases, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), are one of the biggest health problems worldwide. Currently, there is no cure for these diseases. The Gardenia jasminoides fruit is a common herbal medicine in traditional Chinese medicine (TCM), and a variety of preparations are used as treatments for central nervous system (CNS) diseases. Pharmacokinetic studies suggest genipin is one of the main effective ingredients of G. jasminoides fruit extract (GFE). Accumulated research data show that genipin possesses a range of key pharmacological properties, such as anti-inflammatory, neuroprotective, neurogenic, antidiabetic, and antidepressant effects. Thus, genipin shows therapeutic potential for central neurodegenerative diseases. We review the pharmacological actions of genipin for the treatment of neurodegenerative diseases of the CNS. We also describe the potential mechanisms underlying these effects.

U2 - 10.1007/s40263-016-0369-9

DO - 10.1007/s40263-016-0369-9

M3 - Journal article

VL - 30

SP - 889

EP - 897

JO - CNS Drugs

JF - CNS Drugs

SN - 1172-7047

IS - 10

ER -