Final published version
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Titanium surface functionalization with coatings of chitosan and polyphenol-rich plant extracts
AU - Douglas, Timothy E.L.
AU - Kumari, Suman
AU - Dziadek, Kinga
AU - Dziadek, Michal
AU - Abalymov, Anatoly
AU - Cools, Pieter
AU - Brackman, Gilles
AU - Coenye, Tom
AU - Morent, Rino
AU - Mohan, M.K.
AU - Skirtach, Andre G.
PY - 2017/6/1
Y1 - 2017/6/1
N2 - Coating biomedical implant surfaces with biopolymers is an easy and inexpensive way to impart functionalities. Numerous biocompatible biopolymers, including cationic crustacean-derived chitosans, have been used. Here, substrates of Titanium (Ti), commonly used for bone contact applications, were coated with chitosan and one of three polyphenol-rich plant extracts (PPrPE) and characterized physicochemically. Hela cell adhesion and growth of methicillin-resistant Staphylococcus aureus (MRSA) were studied. Chitosan and PPrPE on surfaces were detected by FTIR and XPS. Chitosan coatings, both with and without PPrPE functionalization, did not inhibit MRSA growth and promoted Hela cell adhesion. The effect of PPrPE functionalization remained unclear.
AB - Coating biomedical implant surfaces with biopolymers is an easy and inexpensive way to impart functionalities. Numerous biocompatible biopolymers, including cationic crustacean-derived chitosans, have been used. Here, substrates of Titanium (Ti), commonly used for bone contact applications, were coated with chitosan and one of three polyphenol-rich plant extracts (PPrPE) and characterized physicochemically. Hela cell adhesion and growth of methicillin-resistant Staphylococcus aureus (MRSA) were studied. Chitosan and PPrPE on surfaces were detected by FTIR and XPS. Chitosan coatings, both with and without PPrPE functionalization, did not inhibit MRSA growth and promoted Hela cell adhesion. The effect of PPrPE functionalization remained unclear.
KW - Biomaterials
KW - Thin films
KW - Polymers
KW - Biomimetic
KW - Surfaces
U2 - 10.1016/j.matlet.2017.03.065
DO - 10.1016/j.matlet.2017.03.065
M3 - Journal article
VL - 196
SP - 213
EP - 216
JO - Materials Letters
JF - Materials Letters
SN - 0167-577X
ER -