Final published version
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Use of biologics in SLE
T2 - a review of the evidence from a clinical perspective
AU - Aytan , Jayoti
AU - Bukhari, Marwan A. S.
PY - 2016/5/1
Y1 - 2016/5/1
N2 - With the explosion in biologics use in rheumatology, newer and smarter ways of using these drugs in different diseases have been advocated. SLE has to date been at the back of the biologics algorithms. Recently, the US Food and Drug Administration and European Medicines Evaluation Agency licensed belimumab for use in SLE, the first drug in >30 years. A clinical review of the evidence that underlies the use of belimumab and other biologics in SLE reveals possible reasons why the results are not as spectacular as they are in other diseases.
AB - With the explosion in biologics use in rheumatology, newer and smarter ways of using these drugs in different diseases have been advocated. SLE has to date been at the back of the biologics algorithms. Recently, the US Food and Drug Administration and European Medicines Evaluation Agency licensed belimumab for use in SLE, the first drug in >30 years. A clinical review of the evidence that underlies the use of belimumab and other biologics in SLE reveals possible reasons why the results are not as spectacular as they are in other diseases.
KW - lupus
KW - biologics
KW - review
U2 - 10.1093/rheumatology/kev346
DO - 10.1093/rheumatology/kev346
M3 - Journal article
VL - 55
SP - 775
EP - 779
JO - Rheumatology
JF - Rheumatology
SN - 1462-0324
IS - 5
ER -