Inversion algorithms are available to derive the vertical electron density profile at the midpoint of an oblique sounder path. The techniques open up the possibility of monitoring the ionosphere at otherwise inaccessible locations, such as over sea or inhospitable terrain. A new method of monitoring the ionosphere based on radio tomography can be used to create two-dimensional images of electron density. The results in this paper compare midpoint profiles derived from oblique ionograms with corresponding profiles obtained from tomographic images of electron density and from a vertical ionospheric sounder. The comparisons illustrate the oblique sounder inversion technique and its inherent limitations. The results provide useful information on the complementary nature of the separate ionospheric measurement techniques and have implications for the use of these measurements as inputs to real-time ionospheric models.